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Monoclonal Antibodies

Atezolizumab for Bladder Cancer

Phase 2
Waitlist Available
Research Sponsored by Arjun Balar, MD
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years
Awards & highlights

Study Summary

This trial is testing a combination of two drugs to see if they are effective in treating patients with urothelial carcinoma who cannot take cisplatin-based therapy.

Eligible Conditions
  • Bladder Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Overall survival (OS)
Secondary outcome measures
Assess Safety and Toxicity by CTCAEv4
Disease Control Rate
Duration of Response (DoR)
+2 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Arm A - Atezolizumab + BevacizumabExperimental Treatment2 Interventions
Patients will receive atezolizumab 1200 mg (flat dose) IV plus bevacizumab 15 mg/kg IV every 21 days
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Atezolizumab
2017
Completed Phase 3
~5860
Bevacizumab
2013
Completed Phase 4
~5280

Find a Location

Who is running the clinical trial?

Arjun Balar, MDLead Sponsor
Roche-GenentechIndustry Sponsor
24 Previous Clinical Trials
3,669 Total Patients Enrolled
Hoosier Cancer Research NetworkOTHER
68 Previous Clinical Trials
3,739 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the total number of locations overseeing this clinical trial?

"This trial is accepting participants from 8 distinguished medical sites, such as New york University Clinical Cancer Center of Memphis, West Cancer Center University of Tennessee in Milwaukee, and Froedtert & The Medical College of Wisconsin located in Phoenix. Other locations are also participating."

Answered by AI

Are there any slots still available in this clinical investigation?

"Information hosted on clinicaltrials.gov discloses that this medical trial is not accepting applications at the present time, despite being initially posted in September 2017 and last updated in August 2022. Notwithstanding, there are 835 other research studies recruiting participants as we speak."

Answered by AI

What is the current population size of this experiment?

"This study has since ended recruitment. The original post was published on September 13th 2017, with the latest update occuring August 1st 2022. There are 214 and 621 clinical trials for carcinoma transitional cell and Atezolizumab respectively that are presently open to patients looking for studies to join."

Answered by AI

Are there any other research initiatives that have used Atezolizumab?

"Presently, 621 clinical studies for Atezolizumab are being conducted, with 142 in Phase 3. These trials have a global distribution of 31793 sites; however the majority is based in Taibei, Taiwan."

Answered by AI

Has Atezolizumab been granted government authorization for sale?

"Due to the fact that Atezolizumab is a Phase 2 trial and thus lacks clinical data affirming its efficacy, our team at Power rates this drug's safety as a 2 on a scale of 1 to 3."

Answered by AI

What medical applications is Atezolizumab typically used to treat?

"Atezolizumab is traditionally used to treat non-small cell lung carcinoma, but also has positive effects on conditions such as postoperative recurrent non-squamous NSCLC and recurrent platinum-sensitive epithelial ovarian cancer."

Answered by AI
~2 spots leftby Apr 2025