Adaptive Attention Training for Pediatrics Cancer

Phase-Based Progress Estimates
Univeristy of California, San Francisco, San Francisco, CA
Pediatrics Cancer
Adaptive Attention Training - Behavioral
< 18
All Sexes
Eligible conditions

Study Summary

This study is evaluating whether a novel, adaptive attention training can improve cognitive and behavioral outcomes in pediatric cancer survivors.

See full description

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Pediatrics Cancer

Study Objectives

This trial is evaluating whether Adaptive Attention Training will improve 1 primary outcome, 1 secondary outcome, and 7 other outcomes in patients with Pediatrics Cancer. Measurement will happen over the course of Up to 8 weeks.

Up to 8 weeks
Change in mean performance on a Continuous Performance Task (CPT) over time
Change in mean performance on a Delay Discounting Task over time
Change in mean performance on a computerized Math Fluency Test
Change in mean performance on a computerized Reading Fluency Test
Change in mean scores on a modified Insomnia Severity Index (ISI) Scale over time
Change in mean scores on the Child Self-Control Rating Scale (parent rating) over time
Change in mean scores on the Mindful Attention Awareness Scale (MAAS) over time
Change in mean scores on the Warwick-Edinburgh Mental Well-Being Scale (WEMWBS) over time
Change in sub-test scores on the Adaptive Cognitive Evaluation (ACE) neuropsychological battery

Trial Safety

Safety Progress

1 of 3

Other trials for Pediatrics Cancer

Trial Design

2 Treatment Groups

Low-dose Adaptive Attention Training
1 of 2
Adaptive Attention Training
1 of 2
Active Control
Experimental Treatment

This trial requires 40 total participants across 2 different treatment groups

This trial involves 2 different treatments. Adaptive Attention Training is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Adaptive Attention Training
Participants will complete approximately 15 hours of an at-home training on a novel adaptive attention training program ('Engage'), which will consist of completing thirty, 30-minute sessions over a total of 6-8 weeks.
Low-dose Adaptive Attention Training
Participants will complete approximately 1 hour of at-home training on 'Engage' which consists of two, 30-minute sessions at the beginning and middle of a 6-8 week period.

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: up to 8 weeks
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly up to 8 weeks for reporting.

Closest Location

Univeristy of California, San Francisco - San Francisco, CA

Eligibility Criteria

This trial is for patients born any sex aged 18 and younger. There are 4 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Age 7-17 years at the time of radiation therapy
Have received radiation therapy to the brain or neck
Survival >1 year after diagnosis
Currently not undergoing treatment

Patient Q&A Section

Can pediatrics cancer be cured?

"Survival is possible with treatment. Paediatricians need to be aware of the prognosis, that many patients will die before their symptoms presenting themselves have been recognised. The importance of identifying cancer as early as possible should be reinforced." - Anonymous Online Contributor

Unverified Answer

What causes pediatrics cancer?

"Different types of pediatric cancer can be associated with environmental hazards and genetic mutations. Genetic factors are less significant with brain tumors, although other factors can be associated with the development of brain tumors, such as brain infections." - Anonymous Online Contributor

Unverified Answer

What are the signs of pediatrics cancer?

"Pediatric oncology has developed many diagnostic imaging procedures in order to better recognize [pediatric cancer](, especially in infancy. A good knowledge and ability in applying these procedures is imperative. Besides imaging techniques, pediatric oncology has to be informed of the possibility of a child dying of cancer. The presence of any red or swollen lymph nodes, especially around the neck, are signs of cancer. Also, for example cervical cancer can lead to cervical lymphadenopathy. A lot of other manifestations that require diagnostic imaging include: visceral pleural (lung) effusion, mediastinitis, skeletal involvement (multiple skeletal metastases), and bowel wall lesions. To better identify these findings, the application of radiocontrast can be useful." - Anonymous Online Contributor

Unverified Answer

How many people get pediatrics cancer a year in the United States?

"Pediatric cancers are an increasing focus in cancer screening efforts in the United States. As more adults are screened, it is essential to focus screening efforts on pediatric age groups as this will enable the more efficient use of resources in the long-term. The National Comprehensive Cancer Network has created an online resource that assists with this goal called" - Anonymous Online Contributor

Unverified Answer

What is pediatrics cancer?

"Pediatrics cancer is a cancer of children that forms in the organs. The most common forms are blood cancers and brain, testis and ovarian cancers. There have been a growing number reported paediatric cancer cases since the 1980s and the overall rate appears to be increasing. The causes of these cancers include congenital problems and environmental factors. The prognosis varies however and depends on how aggressive the patient’s cancer is and which organ or tissues it affects. In paediatrics, cancer is one of the leading causes of death." - Anonymous Online Contributor

Unverified Answer

What are common treatments for pediatrics cancer?

"Treatments vary, depending on the tumor type, the child's age, health, and physical ability. Most children have one or more surgeries. Chemotherapy may be given on an outpatient basis. Surgery involves the removal of part of the body; for example, orchiectomy. Radiation therapy is given to the affected parts, such as the brain and bones. In the past, radiation therapy was an in-patient treatment using cobalt 60, then X-rays. Now, this technique has been replaced with computer-controlled radiation therapy delivered over several sessions of daily and weekly treatment. If radiation is needed, it is usually given to the bones or the brain. Children with a brain tumor may also receive chemotherapy." - Anonymous Online Contributor

Unverified Answer

What is the latest research for pediatrics cancer?

"The top 3 most cited research topics in pediatric oncology research are bone marrow transplantation, bone marrow, (both of which are bone malignancies), and brain tumor (nonmalignant tumors that have spread or metastasized from a tumor within the primary site of the tumor). The vast majority of published studies are conducted with children and adolescents. Children and adolescents with cancer represent a growing proportion of the pediatric population, whose lives are being impacted by cancer. Furthermore, pediatric oncology research is ongoing and is expected to be further advanced in the near future. To provide the current, current, and most promising new therapies for pediatric oncology, clinicians may benefit from a comprehensive and multidisciplinary approach." - Anonymous Online Contributor

Unverified Answer

Have there been any new discoveries for treating pediatrics cancer?

"The mainstay of treatment for pediatric oncology has, for many years, been chemotherapy. Most pediatric oncologists take into consideration all pediatric types to be eligible to take on an upcoming pediatric cancer trial before they are offered to do so. However, there are many types of pediatric cancers, so a trial is always appropriate for any type of cancer in an infant or a young child. To find active pediatric cancer trials in your area, you can use Power. To find active types of pediatric cancer, you can also use [" - Anonymous Online Contributor

Unverified Answer

What is the primary cause of pediatrics cancer?

"More than half of the new [pediatric cancer]( cases were due to cancers of the brain and nervous system (21%), and half of these were due to Hodgkin cell lymphoma (12%). In a recent study, findings are consistent with those from an earlier study in which nearly a third of new pediatric oncology cases were due to cancers of the brain." - Anonymous Online Contributor

Unverified Answer

What is the average age someone gets pediatrics cancer?

"At 10 years old, pediatric oncology is usually diagnosed in individuals under the age of 5. However, the age to first diagnosis of pediatric oncology is often at a later age." - Anonymous Online Contributor

Unverified Answer

What is adaptive attention training?

"The AAT used in this study was effective in bringing the brain and attention to the task of moving one finger towards a cued object. Although many studies have demonstrated improvements in patients after use of adaptive attention trainings it is yet to be assessed if these benefits are maintained and if they are beneficial for improving psychosocial functioning." - Anonymous Online Contributor

Unverified Answer

Has adaptive attention training proven to be more effective than a placebo?

"Adaptive attention training is an effective intervention in restoring alertness to pediatric oncology patients with attention-deficit hyperactivity disorder and in improving their performance in everyday situations. Treatment results for pediatric patients with ADHD and cancer are similar to those reported for adult patients with ADHD." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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