Computerized Cognitive Training for Psychosis
(STEP (P4) Trial)
Trial Summary
Do I have to stop taking my current medications to join the trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the study team to understand any specific requirements.
What data supports the effectiveness of the treatment Computerized Cognitive Training for Psychosis?
Research shows that Computerized Cognitive Training (CCT) can improve cognitive performance in people with schizophrenia and healthy older adults. Additionally, Compensatory Cognitive Training (CCT) has shown promise in improving neurocognitive performance and functional capacity in individuals at high risk for psychosis.12345
Is computerized cognitive training safe for humans?
How is Computerized Cognitive Training different from other treatments for psychosis?
Computerized Cognitive Training (CCT) is unique because it uses computer-based exercises to specifically target and improve cognitive functions, such as memory and attention, which are often impaired in psychosis. Unlike traditional therapies, CCT is interactive and can be personalized to the individual's needs, potentially leading to improvements in cognitive performance and daily functioning.12578
What is the purpose of this trial?
The purpose of this study is to examine state representation in individuals aged 15-45 who have been diagnosed with a psychotic illness, as well as young adults who do not have a psychiatric diagnosis. State Representation is our ability to process information about our surroundings. The investigators will complete a clinical trial examining two paradigms of cognitive training.
Research Team
Sophia Vinogradov, M.D.
Principal Investigator
University of Minnesota
Angus MacDonald III, Ph.D.
Principal Investigator
University of Minnesota
Eligibility Criteria
This trial is for individuals aged 15-40 with a recent diagnosis of psychosis or related conditions, who speak English and have an IQ above 70. They must be clinically stable, not pregnant, non-dependent on substances, and without major medical or neurological issues.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Cognitive Training
Participants complete 10 hours of computerized cognitive training over a 3-6 week period
Post-Intervention Follow-up
Participants undergo post-intervention assessments including interviews, questionnaires, neurocognitive assessments, and imaging appointments
Long-term Follow-up
Participants are monitored for changes in cognitive performance and symptoms 5 months after intervention
Treatment Details
Interventions
- Computerized Cognitive Training
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Minnesota
Lead Sponsor
National Institute of Mental Health (NIMH)
Collaborator