Casdatifan Interaction Study in Healthy Subjects
Trial Summary
What is the purpose of this trial?
The purpose of the study is to assess the effects of multiple doses of itraconazole (a strong CYP3A4 inhibitor) on single dose PK of casdatifan in healthy adults and to assess the effects of multiple doses of phenytoin (a strong CYP3A4 inducer) on single dose PK of casdatifan in healthy adults.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. However, since the study involves assessing drug interactions, it's possible that changes to your medication regimen might be required. Please consult with the study team for specific guidance.
What makes the drug Casdatifan unique compared to other treatments?
Casdatifan is unique because it focuses on drug interactions, particularly with food and other substances, which can vary greatly among individuals. This approach is different from many treatments that do not specifically address these interactions, making it potentially safer for people who are more susceptible to side effects from such interactions.12345
Research Team
Medical Director
Principal Investigator
Arcus Biosciences
Eligibility Criteria
This trial is for healthy adults who can participate in a study to understand how casdatifan, a drug under investigation, interacts with other medications. Specific eligibility criteria are not provided.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive casdatifan with itraconazole and phenytoin to assess drug-drug interactions
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Casdatifan
Find a Clinic Near You
Who Is Running the Clinical Trial?
Arcus Biosciences, Inc.
Lead Sponsor