752 Participants Needed

Harm Reduction Kiosk for Substance Use-Related Health Risks

CR
AM
Overseen ByApril M Young, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: April M Young
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial will test a new harm reduction kiosk called KyOSK in rural Appalachia to help people who use drugs stay safer. The kiosk provides clean needles and other supplies to reduce the risk of HIV, hepatitis C, and overdoses. The study aims to determine if this new approach is more effective and cost-efficient.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications.

Is the harm reduction kiosk generally safe for humans?

Harm reduction strategies, including needle exchanges and safe injection sites, have been widely studied and are generally considered safe, with no harmful effects reported in numerous studies. These interventions are designed to reduce the negative consequences of substance use without requiring complete abstinence.12345

How is the harm reduction kiosk treatment different from other treatments for substance use-related health risks?

The harm reduction kiosk is unique because it provides a low-barrier, community-based approach to reducing the risks associated with substance use without requiring abstinence. Unlike traditional treatments that often focus on complete cessation, this approach offers practical tools and resources to minimize harm, making it accessible to individuals who may not be ready or able to stop using substances entirely.12567

What data supports the effectiveness of the harm reduction kiosk treatment?

Research shows that harm reduction strategies, like needle exchanges and safe injection sites, are effective in reducing the negative effects of drug use. These strategies provide additional tools for people who may not be ready to stop using drugs completely, suggesting that harm reduction kiosks could also be beneficial.13689

Who Is on the Research Team?

AM

April M Young, PhD

Principal Investigator

University of Kentucky

Are You a Good Fit for This Trial?

This trial is for adults over 18 living in specific Kentucky counties who've used drugs (other than marijuana, alcohol, and tobacco) to get high via injection or other methods in the past 6 months. It's not open to those under 18 or outside these areas.

Inclusion Criteria

Living in the intervention or comparison county
Engaged in injection or non-injection illicit drug use to get high in the past 6 months (excluding marijuana, alcohol, and tobacco)

Exclusion Criteria

I am under 18 years old.
Current charges of violent crime or stalking
Conviction in the past 10 years of a violent crime (i.e., murder, manslaughter, rape, robbery, and /or aggravated assault) or stalking
See 4 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention Implementation

Implementation of the KyOSK in the intervention county, enhancing the existing SSP model with a harm reduction kiosk

5 years
Continuous access to KyOSK and SSP

Evaluation and Monitoring

Evaluation of the KyOSK's impact on HCV and overdose risk behavior, including assessments of acceptability, appropriateness, fidelity, cost, penetration, and sustainability

5 years
Measured at baseline and then every 6 months

Follow-up

Participants are monitored for safety and effectiveness after the main intervention period

6 months

What Are the Treatments Tested in This Trial?

Interventions

  • Harm reduction kiosk
Trial Overview The study is examining if a harm reduction kiosk can lower risks of HIV, hepatitis C, and drug overdoses among drug users in rural Appalachia. The effectiveness and cost will be evaluated by comparing two counties.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: Syringe Service Program Plus a Harm Reduction Kiosk InterventionExperimental Treatment1 Intervention
Group II: Syringe Service ProgramActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

April M Young

Lead Sponsor

Trials
2
Recruited
990+

National Institute on Drug Abuse (NIDA)

Collaborator

Trials
2,658
Recruited
3,409,000+

Published Research Related to This Trial

The ORION tool, an innovative e-health psychoeducational software, was developed to inform opioid-dependent individuals about overdose risks and identified seven key risk factors related to their behaviors.
While the ORION tool did not significantly change self-efficacy scores in participants, it effectively identified those at higher risk, suggesting that it could be a valuable component of a broader intervention strategy when combined with other support methods.
Engagement in the Overdose RIsk InfOrmatioN (ORION) e-Health Tool for Opioid Overdose Prevention and Self-Efficacy: A Preliminary Study.Carrà, G., Crocamo, C., Humphris, G., et al.[2022]
A qualitative study involving interviews with 20 staff and providers at 3 harm reduction and medical care sites in New York identified 8 key themes for integrating harm reduction into patient care, emphasizing a collaborative and stigma-free environment.
The findings suggest that adopting harm reduction strategies, such as low-threshold care and robust referral networks, can help medical providers effectively engage patients with substance use disorders and improve their overall care experience.
Integrating Harm Reduction into Medical Care: Lessons from Three Models.Chang, JE., Lindenfeld, Z., Hagan, H.[2023]
The ORION project developed an e-health tool designed to educate drug users about overdose risks, emphasizing the importance of evidence-based interventions to improve risk perception and self-efficacy among users.
Initial testing of the ORION tool showed promise in helping users understand their risk factors for overdose, paving the way for further evaluation in clinical settings across Europe to assess its effectiveness and generalizability.
Decision support in addiction: The development of an e-health tool to assess and prevent risk of fatal overdose. The ORION Project.Baldacchino, A., Crocamo, C., Humphris, G., et al.[2022]

Citations

Engagement in the Overdose RIsk InfOrmatioN (ORION) e-Health Tool for Opioid Overdose Prevention and Self-Efficacy: A Preliminary Study. [2022]
Harm reduction therapy: a practice-friendly review of research. [2022]
Integrating Harm Reduction into Medical Care: Lessons from Three Models. [2023]
A scoping review of implementation considerations for harm reduction vending machines. [2023]
Decision support in addiction: The development of an e-health tool to assess and prevent risk of fatal overdose. The ORION Project. [2022]
A review of the efficacy and effectiveness of harm reduction strategies for alcohol, tobacco and illicit drugs. [2022]
Exploring Barriers and Facilitators to Integrating a Harm Reduction Approach to Substance Use in Three Medical Settings. [2023]
Harm reduction: come as you are. [2022]
Harm Reduction in Health Care Settings. [2021]
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