← Back to Search

Cognitive Training for Post-Transplant Cognitive Impairment (cTAG Trial)

N/A

Recruiting

Led By Noha M Sharafeldin

Research Sponsored by University of Alabama at Birmingham

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline

Awards & highlights

cTAG Trial Summary

This trial will test whether it is possible to enroll patients in a study to improve their thinking skills after they have had a hematopoietic cell transplant, as well as whether patients are interested in learning about their genetic risk for cognitive impairment after the transplant.

Who is the study for?

This trial is for adults over 21 who had a bone marrow transplant at UAB, are 3-6 months post-transplant, and can use an internet-connected computer. It's not for those with neurological or major psychiatric disorders, significant sensory/motor issues, color blindness, or recent neuropsychological intervention.Check my eligibility

What is being tested?

The study tests if the Lumosity cognitive training program helps improve brain function in people who've had a bone marrow transplant. Participants will either start training right away or be placed on a waitlist (control group) to compare results.See study design

What are the potential side effects?

Since this trial involves cognitive exercises using Lumosity rather than medication, traditional side effects like you'd see with drugs aren't expected. However, participants may experience fatigue or frustration.

cTAG Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in cognitive function between intervention and wait list control arms from baseline to 12 weeks.

Number of HCT patients completing the 2-arm wait-listed randomized trial of cognitive training intervention for a period of 3 months

Secondary outcome measures

16-item survey to measure genetic factual knowledge at baseline

5 Likert scale survey questionnaire to measure impact of receiving genetic risk information on intervention adherence

5 Likert scale survey questionnaire to measure impact of receiving genetic risk information on intervention uptake

+2 more

cTAG Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: InterventionExperimental Treatment1 Intervention

The arm will begin the Lumosity program at enrollment in the study.

Group II: Wait List ControlActive Control1 Intervention

The arm will begin the Lumosity program 3 months after enrollment in the study.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Lumosity

2016

N/A

~50

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of Alabama at BirminghamLead Sponsor

1,590 Previous Clinical Trials

2,281,422 Total Patients Enrolled

Noha M SharafeldinPrincipal InvestigatorUniversity of Alabama at Birmingham

Media Library

Lumosity Clinical Trial Eligibility Overview. Trial Name: NCT03094026 — N/A

Blood Cancers Research Study Groups: Intervention, Wait List Control

Blood Cancers Clinical Trial 2023: Lumosity Highlights & Side Effects. Trial Name: NCT03094026 — N/A

Lumosity 2023 Treatment Timeline for Medical Study. Trial Name: NCT03094026 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What objectives does this research endeavor seek to accomplish?

"This clinical trial will track the primary outcome of how many haematopoietic stem cell transplant (HCT) patients complete a 2-arm waitlisted randomised cognitive training intervention over a 3 month period. Secondary outcomes being considered include assessing the effect size of key predictors such as age, gender and socio-economic status on participants genetic factual knowledge; patient ratings collected via 5 Likert scale survey questionnaires to measure impact of receiving genetic risk information on intervention uptake, and importance in recieving this kind of infomation post HCT."

Answered by AI

Are researchers currently signing up new participants for this experiment?

"As reflected on clinicaltrials.gov, this trial is actively enrolling patients with the original posting dating back to August 21st of 2017 and was last updated recently in April 25th 2022."

Answered by AI

To what extent have participants been recruited for this investigation?

"Affirmative. The clinical trial is actively seeking participants, with 60 individuals needing to be recruited from one site. This medical research was initially posted on August 21st 2017 and recently updated on April 25th 2022 according to information available at clinicaltrials.gov."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Cognitive Training Intervention and Attitudes Towards Genetics

Noha Mohamed Sharafeldin 2017. "Cognitive Training Intervention and Attitudes Towards Genetics". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03094026.

All > Blood Cancer