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HIIT Exercise for Brain Cancer Survivors (HYPE Trial)

N/A

Recruiting

Led By Christina Dieli-Conwright, PhD, MPH

Research Sponsored by Dana-Farber Cancer Institute

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up from baseline to week 16, up to 32 weeks

Awards & highlights

HYPE Trial Summary

This trial will test whether an exercise program can improve physical, mental and emotional health for young adult survivors of pediatric brain tumors.

Who is the study for?

This trial is for young adults aged 18-39 who survived pediatric brain tumors, are at least two years post-treatment, and currently do little structured exercise. They must be medically cleared for exercise, not smoke or vape, agree to use contraception if applicable, and be willing to travel for data collection. Those with uncontrolled diseases or active malignancies cannot join.Check my eligibility

What is being tested?

The study tests a virtual 16-week high-intensity interval training (HIIT) program against a control group to see if it improves physical, cognitive, and emotional health in survivors of pediatric brain tumors.See study design

What are the potential side effects?

While the trial does not involve medication with side effects typical of drugs, HIIT can cause muscle soreness, fatigue or injury especially if participants are not accustomed to intense physical activity.

HYPE Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ from baseline to week 16, up to 32 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~from baseline to week 16, up to 32 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and from baseline to week 16, up to 32 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Attendance of Exercise Sessions

Barriers to Exercise Adherence

Completion in Minutes of Exercise Sessions

+2 more

Secondary outcome measures

ActiGraph - Physical Activity Monitoring

Body Composition

Cardiorespiratory Fitness

+9 more

HYPE Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: HIIT Exercise Program GroupExperimental Treatment1 Intervention

Participants will be randomly assigned to the HIIT exercise group and receive: 3x weekly for 16 week home-based virtually supervised High-Intensity Interval Training. 16-week self-directed exercise follow up period. 3 On-site visits at Week 1, 18 and 34 for assement testing and completion of questionnaires

Group II: Control GroupActive Control1 Intervention

Participants will be randomly assigned to the HIIT waitlist control group and receive: Daily usual activities 2 On-site visits at Week 1, and 18 for assement testing and completion of questionnaires Option to complete 16 week, 3x weekly HIIT exercise program after initial 16 week period.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Pedals For PediatricsUNKNOWN

Dana-Farber Cancer InstituteLead Sponsor

1,079 Previous Clinical Trials

340,947 Total Patients Enrolled

Stahl Family Charitable FoundationUNKNOWN

Media Library

High-Intensity Interval Training (HIIT) Clinical Trial Eligibility Overview. Trial Name: NCT05740839 — N/A

Brain Tumor Research Study Groups: HIIT Exercise Program Group, Control Group

Brain Tumor Clinical Trial 2023: High-Intensity Interval Training (HIIT) Highlights & Side Effects. Trial Name: NCT05740839 — N/A

High-Intensity Interval Training (HIIT) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05740839 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are geriatric patients being admitted for this clinical trial?

"This trial is exclusively for adults aged 18 to 39. For those who are younger or older, there are 79 trials available for under-18s and 331 for over-65s."

Answered by AI

Who is most likely to be a suitable participant in this investigation?

"Qualified applicants for this trial should have pediatric brain tumors and be between 18 to 39 years old. A total of 30 participants will be selected for the study."

Answered by AI

Are there any vacancies available in this clinical research study?

"According to the clinicaltrials.gov website, this clinical trial is no longer actively enrolling participants. The initial posting date was May 1st 2023 and the latest update happened on February 13th of that same year. However, there are still 389 other trials seeking volunteers at this time."

Answered by AI

What aims is this trial attempting to accomplish?

"This 16-week trial will monitor changes in the total minutes of exercise sessions. Secondary metrics to be recorded include cardiorespiratory fitness (measured through a VO2 max cycle test), muscular strength (evaluated via 10-repetition maximum tests) and body composition (assessed using bioelectrical impedance analysis). Blood pressure readings, taken twice per arm with at least one minute between measurements, are also collected."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

High-Intensity Interval Exercise in Young Adult Survivors of Pediatric Brain Tumors: A Pilot Feasibility Study

Christina Dieli-Conwright, PhD 2023. "High-Intensity Interval Exercise in Young Adult Survivors of Pediatric Brain Tumors: A Pilot Feasibility Study". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05740839.

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