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MTP Block vs Paravertebral Block for Pain Relief in Breast Cancer Surgery

N/A

Recruiting

Led By Ioana Costache, MD

Research Sponsored by Ottawa Hospital Research Institute

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 48 hours

Awards & highlights

Study Summary

This trial will compare the pain-relieving effects of a MTP block to a thoracic paravertebral block and to no block.

Who is the study for?

This trial is for English or French-speaking individuals scheduled for major breast surgery, with a BMI under 30 and an ASA physical status of I-III. It's not suitable for those who've had previous breast surgery on the same side, have nerve issues in the chest, can't have regional anesthesia, refuse this type of pain control, use opioids regularly, suffer from chronic pain disorders or cannot consent.Check my eligibility

What is being tested?

The study is testing how well a new pain-blocking procedure called MTP block works compared to no intervention (control) and another established method known as thoracic paravertebral block (PVB). Participants will be randomly assigned to one of these three groups during their breast cancer surgery.See study design

What are the potential side effects?

While specific side effects are not listed here, typical risks may include discomfort at the injection site, potential nerve damage or infection from the blocks used in both MTP and PVB procedures. The control group would not experience these since they do not receive these interventions.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 48 hours

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~48 hours

This trial's timeline: 3 weeks for screening, Varies for treatment, and 48 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Postoperative analgesia during the first 24 hours.

Secondary outcome measures

Post-operative quality of recovery during the first 24 hours.

Trial Design

3Treatment groups

Experimental Treatment

Active Control

Placebo Group

Group I: MTP block groupExperimental Treatment1 Intervention

MTP blocks with 0.5% ropivacaine and epinephrine 2.5 mcg/mL

Group II: PVB groupActive Control1 Intervention

paravertebral blocks with 0.5% ropivacaine and epinephrine 2.5 mcg/mL

Group III: control groupPlacebo Group1 Intervention

local anesthetic infiltration subcutaneous 1% lidocaine

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Ottawa Hospital Research InstituteLead Sponsor

561 Previous Clinical Trials

2,785,541 Total Patients Enrolled

2 Trials studying Acute Pain

172 Patients Enrolled for Acute Pain

Ioana Costache, MDPrincipal InvestigatorOttawa Hospital, Ottawa Hospital Research Institute

Media Library

Control Group Clinical Trial Eligibility Overview. Trial Name: NCT03713255 — N/A

Acute Pain Research Study Groups: PVB group, MTP block group, control group

Acute Pain Clinical Trial 2023: Control Group Highlights & Side Effects. Trial Name: NCT03713255 — N/A

Control Group 2023 Treatment Timeline for Medical Study. Trial Name: NCT03713255 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is senior participation accepted in this research endeavor?

"This medical trial necessitates that enrollees must be aged between 18 and 65. Alternately, there are 124 trials appropriate for individuals below the age of consent and 2706 studies available to those over retirement age."

Answered by AI

Are any new participants being accepted into this experiment?

"Affirmative, the details on clinicaltrials.gov reveal that this investigation is currently seeking participants. This trial was first announced on January 1st 2020 and has recently been modified as of September 29th 2022. The research team needs to recruit 150 patients from one single site."

Answered by AI

What criteria must be met for enrolment in this experiment?

"This medical trial seeks 150 participants, ranging in age from 18 to 65 years old and who have been diagnosed with breast cancer. Additionally, those wishing to participate must be scheduled for major surgery, classified as either ASA I-III on the physical status scale, and possess a BMI of below 30kg/m2."

Answered by AI

What is the population size for this research undertaking?

"Affirmative. Clinicaltrials.gov's records reveal that the clinical trial, which was initially posted on January 1st 2020 and recently updated on September 29th 2022, is actively recruiting patients. This medical experiment requires 150 participants to be sourced from a single site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Mid-point Transverse Process to Pleura Block for Breast Cancer Surgery: A Randomized Controlled Trial

2020. "Mid-point Transverse Process to Pleura Block for Breast Cancer Surgery: A Randomized Controlled Trial". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03713255.