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Trial Phase
Trial Status
Paid Participation
64 Diabetes Trials near Springfield, IL
Power is an online platform that helps thousands of Diabetes patients discover FDA-reviewed trials every day. Every trial we feature meets safety and ethical standards, giving patients an easy way to discover promising new treatments in the research stage.
Learn More About PowerTirzepatide vs Dulaglutide for Type 2 Diabetes
Trial Details
Key Eligibility Criteria
13299 Participants Needed
Eversense CGM for Diabetes
Trial Details
Key Eligibility Criteria
925 Participants Needed
Ladarixin for Type 1 Diabetes
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Key Eligibility Criteria
140 Participants Needed
CagriSema for Diabetic Neuropathy
Trial Details
Key Eligibility Criteria
134 Participants Needed
Tirzepatide for Type 1 Diabetes and Obesity
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Key Eligibility Criteria
905 Participants Needed
Retatrutide for Obesity
Trial Details
Key Eligibility Criteria
10000 Participants Needed
Trevogrumab + Garetosmab + Semaglutide for Obesity
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Key Eligibility Criteria
999 Participants Needed
RYBELSUS® for Type 2 Diabetes
Trial Details
Key Eligibility Criteria
1262 Participants Needed
Inclisiran for Cardiovascular Disease Prevention
Trial Details
Key Eligibility Criteria
14012 Participants Needed
NNC0519-0130 for Type 2 Diabetes
Trial Details
Key Eligibility Criteria
288 Participants Needed
AT-001 for Diabetic Cardiomyopathy
Trial Details
Key Eligibility Criteria
675 Participants Needed
Tremelimumab for Mesothelioma
Trial Details
Key Eligibility Criteria
571 Participants Needed
Finerenone + Empagliflozin for Chronic Kidney Disease and Type 2 Diabetes
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Key Eligibility Criteria
1664 Participants Needed
Stable Isotopes for Obesity
Trial Details
Key Eligibility Criteria
8 Participants Needed
Finerenone for Chronic Kidney Disease in Type 1 Diabetes
Trial Details
Key Eligibility Criteria
220 Participants Needed
Tirzepatide for Type 2 Diabetes
Trial Details
Key Eligibility Criteria
780 Participants Needed
BMF-219 for Type 2 Diabetes
Trial Details
Key Eligibility Criteria
414 Participants Needed
LY3209590 for Type 2 Diabetes in Children
Trial Details
Key Eligibility Criteria
22 Participants Needed
Auricular Vagal Nerve Stimulation for Spinal Fusion Surgery
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Key Eligibility Criteria
50 Participants Needed
Texting Intervention for Gestational Diabetes
Trial Details
Key Eligibility Criteria
185 Participants Needed
Why Other Patients Applied
"I have had type 2 diabetes for some time now and would love to be part of a study... should the study drug work out as a successful treatment, then I would be glad to be one of the first patients in line!"
"I have already lost part of a leg to an infection. I want to try to get this horrific condition under control and get back to my life. It's taken enough."
"I've been in pain for years. It's been crippling and has massively impacted my life. I want to be free. Diabetes changed everything at 15. Diabetic Type 1 for 20 years. SEVERE Peripheral Neuropathy onset 7-8 years in. Have been living with it since. Have tried every drug, everything. Gaba, lyrica, all opioids, electrical current therapy, massages, acupuncture, cupping, everything. Currently taking low dose of duloxetine, have an insulin pump but its not good enough. Want to try a cutting-edge med."
"Looking for better ways to manage my diabetes, high blood pressure and overall health. Hoping to improve my health all together in order to have a better life & to enjoy my children & grandchildren."
"Years ago, Metformin didn't help. I'm currently on Rybelsus & Farxiga. Not doing me much good. My insurance won't cover any of the injectables. Excited to try something new."
AMX0035 for Wolfram Syndrome
Trial Details
Key Eligibility Criteria
12 Participants Needed
DIAGNODE-3 study for recently diagnosed type I diabetes
Trial Details
Key Eligibility Criteria
330 Participants Needed
Trial Details
Key Eligibility Criteria
1500 Participants Needed
Weekly vs Daily Insulin for Type 1 Diabetes
Trial Details
Key Eligibility Criteria
877 Participants Needed
Vicadrostat + Empagliflozin for Type 2 Diabetes and Hypertension
Trial Details
Key Eligibility Criteria
11800 Participants Needed
CagriSema for Type 2 Diabetes
Trial Details
Key Eligibility Criteria
1023 Participants Needed
Naltrexone + Bupropion for Obesity
Trial Details
Key Eligibility Criteria
8600 Participants Needed
LY3938577 for Type 2 Diabetes
Trial Details
Key Eligibility Criteria
100 Participants Needed
AZD5004 for Type 2 Diabetes
Trial Details
Key Eligibility Criteria
406 Participants Needed
Ketogenic Diet for Type 1 Diabetes
Trial Details
Key Eligibility Criteria
58 Participants Needed
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We started Power when my dad was diagnosed with multiple myeloma, and I struggled to help him access the latest immunotherapy. Hopefully Power makes it simpler for you to explore promising new treatments, during what is probably a difficult time.
Frequently Asked Questions
How much do Diabetes clinical trials in Springfield, IL pay?
Each trial will compensate patients a different amount, but $50-100 for each visit is a fairly common range for Phase 2–4 trials (Phase 1 trials often pay substantially more). Further, most trials will cover the costs of a travel to-and-from the clinic.
How do Diabetes clinical trials in Springfield, IL work?
After a researcher reviews your profile, they may choose to invite you in to a screening appointment, where they'll determine if you meet 100% of the eligibility requirements. If you do, you'll be sorted into one of the treatment groups, and receive your study drug. For some trials, there is a chance you'll receive a placebo. Across Diabetes trials in Springfield, IL 30% of clinical trials have a placebo. Typically, you'll be required to check-in with the clinic every month or so. The average trial length in Springfield, IL for Diabetes is 12 months.
How do I participate in a study as a "healthy volunteer"?
Not all studies recruit healthy volunteers: usually, Phase 1 studies do. Participating as a healthy volunteer means you will go to a research facility in Springfield, IL several times over a few days or weeks to receive a dose of either the test treatment or a "placebo," which is a harmless substance that helps researchers compare results. You will have routine tests during these visits, and you'll be compensated for your time and travel, with the number of appointments and details varying by study.
What does the "phase" of a clinical trial mean?
The phase of a trial reveals what stage the drug is in to get approval for a specific condition. Phase 1 trials are the trials to collect safety data in humans. Phase 2 trials are those where the drug has some data showing safety in humans, but where further human data is needed on drug effectiveness. Phase 3 trials are in the final step before approval. The drug already has data showing both safety and effectiveness. As a general rule, Phase 3 trials are more promising than Phase 2, and Phase 2 trials are more promising than phase 1.
Do I need to be insured to participate in a Diabetes medical study in Springfield, IL?
Clinical trials are almost always free to participants, and so do not require insurance. The only exception here are trials focused on cancer, because only a small part of the typical treatment plan is actually experimental. For these cancer trials, participants typically need insurance to cover all the non-experimental components.
What are the newest Diabetes clinical trials in Springfield, IL?
Most recently, we added LY3938577 for Type 2 Diabetes, Auricular Vagal Nerve Stimulation for Spinal Fusion Surgery and Stable Isotopes for Obesity to the Power online platform.
What is the best treatment for diabetes?
There isn’t one “best” therapy—think of diabetes care as two layers. First, everyone benefits from diabetes education, a balanced diet, regular activity, and routine monitoring. Second, medicines are chosen by diabetes type and other health issues: type 1 always needs insulin (preferably with a continuous glucose monitor or hybrid pump), while type 2 usually starts with metformin plus lifestyle changes and, if more help is needed, adds a GLP-1 or SGLT2 drug (especially when heart, kidney, or weight problems exist) before considering insulin. Work with your healthcare team to revisit these steps every few months so treatment keeps pace with your goals and any new health changes.
How much weight do you need to lose to reverse type 2 diabetes?
Most studies find that you need to shed about 10–15 % of your starting weight—roughly 15 kg (33 lb) for an average-sized adult—to give yourself the best shot at putting type-2 diabetes into remission (normal sugars without diabetes pills). The closer you are to diagnosis and the more weight you keep off—especially if you can pass the 15 kg mark—the higher the odds (up to 80 % in some trials), while smaller losses still improve blood sugar but rarely achieve full remission. Work with your healthcare team to choose a safe approach (intensive diet program, GLP-1 medications, or bariatric surgery) and to monitor that blood-sugar targets stay on track once the weight comes off.
Can diabetics still get Ozempic?
Yes—if you have type-2 diabetes and meet NICE criteria (poor glucose control despite other drugs, or need for weight loss/heart-protection), your GP or diabetes nurse can still prescribe Ozempic; it is not used for type-1 diabetes, pregnancy, or in children. The practical hurdle is the current UK supply shortage, so existing users should order repeats early and stay in touch with their pharmacist, while new patients may need to start a similar medicine (e.g., dulaglutide) until stock returns.
When will oral insulin be available?
No insulin pill has been approved yet. The most advanced candidates (such as insulin tregopil and ORMD-0801) are still redesigning or preparing large Phase 3 studies, and newer “chocolate-capsule” nano-formulations have not even begun human trials until at least 2025. If upcoming studies succeed, regulatory review and manufacturing mean that everyday prescription use is unlikely before the late-2020s at the earliest.
Why is type 2 diabetes not curable?
Type 2 diabetes isn’t considered curable because its root problems—body-wide insulin resistance and gradual loss of insulin-producing β-cells—can return whenever weight or lifestyle slips, and adult β-cells don’t fully regrow once lost. Big, sustained weight loss (through diet, bariatric surgery, or powerful medications) can put the disease into remission for years, but the underlying susceptibility remains, which is why regular follow-up and healthy habits must continue even when blood sugar is normal.
Can I stop taking metformin when my sugar is back to normal?
Normal readings don’t necessarily mean diabetes is cured; for many people the numbers stay normal only because metformin is on board, and stopping it without a plan can let sugars creep back up. Talk with your clinician about whether you truly meet “remission” criteria (HbA1c < 6.5 % for at least 6 months, stable weight, good kidney function); if so, you can try a monitored dose-reduction, check home glucose and repeat labs in 3 months, and restart the drug promptly if levels rise. In short, never quit metformin on your own—make it a shared, step-by-step decision that includes a taper and clear follow-up.
Can a person fully recover from diabetes?
Type 1 diabetes cannot presently be cured; people need lifelong insulin. In type 2 diabetes, some individuals—especially soon after diagnosis—can achieve remission (normal blood-sugar readings without diabetes medicines) through substantial, sustained weight loss or bariatric surgery, but the underlying tendency can return, so regular check-ups remain essential. So while you may control or even “switch off” type 2 diabetes for a time, no form of diabetes is considered permanently gone.
Which country has the cure for diabetes?
No country has an approved, take-home “cure” for diabetes; the Chinese cell-therapy result you may have seen was a one-patient, early-stage experiment that still needs larger trials and regulatory review. Worldwide teams—from China to the United States, Canada, Europe and beyond—are testing stem-cell implants, gene editing and immune therapies, but for now the proven way to stay healthy is tight glucose monitoring, modern medications (e.g., metformin, GLP-1 or insulin) and lifestyle changes, with bariatric surgery offering remission for some people with type 2 diabetes. Stay alert for peer-reviewed trial results and discuss any experimental option with your diabetes specialist before pursuing treatment abroad.
What is the record trial for diabetes?
RECORD (Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycaemia in Diabetes) was a 5-year study of 4,458 adults with type 2 diabetes that compared adding rosiglitazone to metformin or a sulfonylurea versus the standard metformin-plus-sulfonylurea combination. It showed no overall difference in cardiovascular deaths or hospitalisations (hazard ratio 0.99), but rosiglitazone roughly doubled the risk of heart-failure events and increased bone fractures; these safety concerns, rather than glucose control, ultimately led regulators and doctors to curb use of the drug.
What is the A1C goal for a 70 year old?
For a 70-year-old who already has diabetes, guidelines use a sliding scale: aim below about 7–7.5 % if the person is otherwise healthy and independent, below 8 % if they have multiple illnesses or mild functional decline, and up to 8.5 % if they are frail or in long-term care—these higher limits reduce the risk of dangerous low-blood-sugar episodes. If the 70-year-old is only being screened, the usual cut-offs still apply (normal < 5.7 %, pre-diabetes 5.7-6.4 %, diabetes ≥ 6.5 % confirmed). Work with the healthcare team to choose the target that balances day-to-day safety with long-term benefit.