Intervention Group for Obesity

Phase-Based Progress Estimates
2
Effectiveness
3
Safety
Obesity+5 MoreSemaglutide 2.4mg - Drug
Eligibility
18 - 75
All Sexes
What conditions do you have?
Select

Study Summary

This trial is testing an anti-obesity medication to see how well it works in helping people lose weight and keep it off. The results could help lead to new medications for obesity.

Eligible Conditions
  • Obesity
  • Weight Loss
  • Overweight or Obesity

Video Summary

Treatment Effectiveness

Effectiveness Progress

2 of 3
This is further along than 85% of similar trials

Study Objectives

1 Primary · 1 Secondary · Reporting Duration: Change between baseline and month four of treatment.

Change between baseline and final study visit, seven months post baseline.
Assessment of weight loss.
Change between baseline and month four of treatment.
Food Addiction Assessment

Trial Safety

Safety Progress

3 of 3
This is further along than 85% of similar trials

Trial Design

2 Treatment Groups

Intervention Group
1 of 2
Control Group
1 of 2

Active Control

Non-Treatment Group

100 Total Participants · 2 Treatment Groups

Primary Treatment: Intervention Group · Has Placebo Group · Phase 3

Control Group
Drug
PlaceboComparator Group · 1 Intervention: Placebo · Intervention Types: Drug
Intervention Group
Drug
ActiveComparator Group · 1 Intervention: Semaglutide 2.4mg · Intervention Types: Drug

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: change between baseline and month four of treatment.

Who is running the clinical trial?

Loma Linda UniversityLead Sponsor
285 Previous Clinical Trials
257,925 Total Patients Enrolled
8 Trials studying Obesity
892 Patients Enrolled for Obesity
Novo Nordisk A/SIndustry Sponsor
1,405 Previous Clinical Trials
2,308,939 Total Patients Enrolled
117 Trials studying Obesity
127,590 Patients Enrolled for Obesity
Warren Peters, MD, MPHLead Sponsor
Warren Peters, MDPrincipal InvestigatorLoma Linda University
1 Previous Clinical Trials
50 Total Patients Enrolled
1 Trials studying Obesity
50 Patients Enrolled for Obesity

Eligibility Criteria

Age 18 - 75 · All Participants · 4 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
I identify as being of Hispanic/Latino ethnicity.
People between the ages of 18 and 75 years old.
are conducted Can agree to taking part in a trial before any activities related to the trial are conducted.

Who else is applying?

What state do they live in?
California38.5%
Georgia7.7%
Ohio7.7%
Other46.2%
How old are they?
18 - 65100.0%
What site did they apply to?
Loma Linda University Health100.0%
What portion of applicants met pre-screening criteria?
Met criteria41.7%
Did not meet criteria58.3%
Why did patients apply to this trial?
  • "I’ve had a life long battle with obesity. I need help!"
  • "I have tried everything to lose weight for 20 years and I just want to get it off and keep it off."
  • "I’ve tried everything except injectable medication and surgery to get this weight off. I’ve tried all the stimulants that can be prescribed and they work for about a week and that’s it. Looking for a long term solution."
  • "I have tried everything to get this weight off. But since menopause it’s gotten so much worse that it’s made my degenerative disc disease so painful.. I also have rheumatoid arthritis. I would hope the injections would help to shed pounds so that I could participate in physical activity."
  • "I have fought my weight just about my whole life but always kept it under control with discipline. But since I’ve went thru menopause and gotten older it’s impossible to loose. I’m 5-3 240 lbs and I have severe back issues and rheumatoid arthritis and my weight makes it impossible to be active at all."
What questions have other patients asked about this trial?
  • "Can this be done remotely?"
  • "Can I participate virtually?"
  • "Will I have to travel out of state? If so, will I be responsible for expenses?"
How many prior treatments have patients received?
066.7%
116.7%
3+16.7%

How responsive is this trial?

Most responsive sites:
  1. Loma Linda University Health: < 48 hours
Average response time
  • < 2 Days
Typically responds via
Phone Call100.0%