← Back to Search

Sphingosine 1-phosphate receptor modulator

Etrasimod for Alopecia Areata

Phase 2
Waitlist Available
Research Sponsored by Pfizer
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to approximately 56 weeks (24-weeks of double-blind treatment period, 28-weeks of open-label extension period, and 4-weeks of safety follow-up period)
Awards & highlights

Study Summary

This trial is testing a new medication for people with moderate to severe hair loss due to alopecia areata.

Eligible Conditions
  • Alopecia Areata

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to approximately 56 weeks (24-weeks of double-blind treatment period, 28-weeks of open-label extension period, and 4-weeks of safety follow-up period)
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to approximately 56 weeks (24-weeks of double-blind treatment period, 28-weeks of open-label extension period, and 4-weeks of safety follow-up period) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Percent Change From Baseline in Severity of Alopecia Tool (SALT)
Secondary outcome measures
Change From Baseline in SALT
Number and Severity of Adverse Events (Double-Blind Treatment Period and Open-Label Extension Period)
Proportion of Participants Achieving ≥30% Improvement From Baseline in SALT
+2 more

Side effects data

From 2022 Phase 3 trial • 42 Patients • NCT04706793
14%
Headache
11%
Malaise
11%
Pyrexia
7%
Colitis ulcerative
7%
Vaccination site pain
4%
COVID-19
4%
Contusion
4%
Back pain
100%
80%
60%
40%
20%
0%
Study treatment Arm
Placebo Comparator: Placebo
Experimental: Etrasimod 2 mg

Trial Design

3Treatment groups
Experimental Treatment
Placebo Group
Group I: Etrasimod 3 mgExperimental Treatment1 Intervention
Group II: Etrasimod 2 mgExperimental Treatment1 Intervention
Group III: PlaceboPlacebo Group1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Etrasimod
2020
Completed Phase 3
~1350

Find a Location

Who is running the clinical trial?

PfizerLead Sponsor
4,567 Previous Clinical Trials
10,911,793 Total Patients Enrolled
13 Trials studying Alopecia Areata
85,954 Patients Enrolled for Alopecia Areata
Arena is a wholly owned subsidiary of PfizerIndustry Sponsor
10 Previous Clinical Trials
2,565 Total Patients Enrolled
Arena PharmaceuticalsLead Sponsor
28 Previous Clinical Trials
5,796 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the upper limit of participants in this clinical investigation?

"In order to fulfill the requirements of this clinical trial, 78 patients that meet specific selection criteria must participate. These individuals can enroll in one of two sites: Torrance Clinical Research Institute, Inc located in Lomita, California or Central Sooner Research based out of Norman, Oklahoma."

Answered by AI

Are there still opportunities for participants to join this experiment?

"Affirmative. The information accessible on clinicaltrials.gov suggests that this research is actively recruiting participants, with the original post dating back to August 31st 2020 and most recent update occurring in March 2nd 2022. To fulfill the requirements of this trial, 78 patients need to be recruited from 29 individual sites."

Answered by AI

Does the FDA sanction the utilization of Etrasimod?

"Our team has rated the safety of Etrasimod as a 2, which indicates that there is preliminary data suggesting it to be safe but without any efficacy tests yet conducted."

Answered by AI

How many medical facilities in the city are currently conducting this research?

"The Torrance Clinical Research Institute, Inc in Lomita, California, Central Sooner Research in Norman Oklahoma and the California Dermatology & Clinical Reserach Institute in Encinitas Maryland are among the 30 medical centres running this trial."

Answered by AI

Do I meet the qualifications for this clinical trial?

"To be considered for this medical trial, applicants must have alopecia areata and fall in the 18-70 age bracket. A total of 78 participants will ultimately take part."

Answered by AI

Is this research endeavor open for enrollment to those above the age of 35?

"As predetermined by the selection criteria, only adults aged between 18 and 70 can be enrolled in this clinical trial."

Answered by AI

Is this experimental research the inaugural effort of its type?

"Currently, 7 clinical trials for Etrasimod are taking place in 369 municipal areas and 50 sovereign nations. The primary study was conducted by Arena Pharmaceuticals 3 years ago with 912 participants, which has since been followed up by 18,322 other experiments. This set of tests have concluded their Phase 3 drug approval process."

Answered by AI

What precedent has been established with regards to Etrasimod's medical experiments?

"Etrasimod has been studied since 2019, when it was first assessed at Centralny Szpital Kliniczny MSW w Warszawie. Since then, there have been 18322 completed clinical trials and 7 that are still actively recruiting participants; many of these experiments take place in Lomita, California."

Answered by AI

Who else is applying?

What state do they live in?
Georgia
Tennessee
How old are they?
18 - 65
What site did they apply to?
Advance Medical Research PC
University of California
What portion of applicants met pre-screening criteria?
Met criteria
How many prior treatments have patients received?
3+
Recent research and studies
clinicaltrials.govStudy
Safety and Efficacy of Oral Etrasimod in Adult Participants With Moderate-to-Severe Alopecia Areata
2020. "Safety and Efficacy of Oral Etrasimod in Adult Participants With Moderate-to-Severe Alopecia Areata". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04556734.
~17 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top