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olaparib for Breast
Study Summary
This trial will test how well olaparib works in treating patients with advanced cancer who have a confirmed genetic BRCA1 and/or BRCA2 mutation.
- Breast
- Pancreatic
- Tumors
- Ovarian
- Prostate
Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2023 Phase 3 trial • 387 Patients • NCT02987543Trial Design
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Who is running the clinical trial?
Frequently Asked Questions
Are there any opportunities for participation in this research endeavor?
"Clinicaltrials.gov displays that this research project, which began on February 21st 2010 and was last updated October 4th 2022, is not seeking participants currently; however there are 195 other medical trials actively recruiting patients at the present time."
How many participants can join this experiment?
"At this juncture, recruitment for the clinical trial has ceased. The study was first made available on February 21st 2010 and last updated October 4th 2022. If you are looking to participate in further medical studies, 7 trials related to prostate cancer and 188 related to olaparib currently have open enrolment programs."
Is this a pioneering clinical trial?
"Presently, there are 188 separate clinical investigations of olaparib active in 59 countries and 1468 cities. The first assessment occurred back in 2005 and was sponsored by AstraZeneca; it involved 98 individuals and achieved Phase 1 drug approval status. In the 15 years since then, 63 additional trials have been conducted."
Has olaparib been given the stamp of approval by the FDA?
"Considering the Phase 2 status of olaparib, which has data to support safety but not yet efficacy, our team at Power assigned it a rating of 2."
Is the enrollment criterion for this trial restricted to seniors or are younger individuals able to participate?
"This clinical trial is available to adults that are over 18 years old and no more than 130 years of age."
Could you supply a summary of prior research involving olaparib?
"At present, there are 188 clinical trials actively studying olaparib with 27 of them in the final stage. While Houston is a major hub for these studies, they span 9250 sites throughout the world."
For whom is this medical experiment best suited?
"This particular medical study is searching for 298 subjects aged 18 to 130 with prostate cancer, who further have confirmed deleterious or suspected deleterious BRCA mutations. Additionally, these participants must also have a malignant solid tumour without an existing treatment protocol and at least one measureable lesion that can be accurately assessed via CT/MRI scans."
What is the common purpose of olaparib consumption?
"Olaparib is popularly prescribed to treat advanced forms of cancer, such as malignant neoplasm of the ovary and primary peritoneal cancer. It can also be beneficial for managing hallucinations or somatic symptoms."
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