PBI-0451 (Pomotrelvir) for COVID-19

"Mercy Family Clinic in Houston, Texas, Infectious disease Consultants of the Treasure Coast in Sebastian, Mississippi and Safe Haven Clinical Research in Clinton California are some of the 40 sites that have opened recruiting for this trial."

"To join this trial, potential participants must be within the appropriate age range of 18 to 64. For those under 18 and over 65 respectively, there are 137 and 899 other clinical trials available for them."

"Clinicaltrials.gov confirms that this medical study, which was launched on September 21st 2022, is actively seeking participants. The protocol has been recently revised as of November 11th 2022."

"The safety of PBI-0451 has been gauged at a 2 on our Power scale, as this is currently an experimental Phase 2 trial with limited clinical data confirming its efficacy."

"This trial is recruiting 210 suitable patients who are currently suffering from COVID-19 and aged between 18 to 64. To be eligible, applicants must have had symptoms for no longer than 5 days before enrolment with a positive SARS-CoV-2 test within 24 hours of randomisation. Furthermore, it's mandatory that the patient has at least 2 acute symptoms as identified by the investigator via questionnaire; male participants must refrain from sperm donation during treatment and 90 days after completing study drug administration; receive primary vaccination series recommended by Centers for Disease Control and Prevention (CDC). Additionally, all female partakers need to pass a negative serum or urine"

"The study sponsor, Pardes Biosciences, Inc., must recruit 210 eligible patients to run the trial. The process is taking place in various locations such as Mercy Family Clinic of Houston, Texas and Infectious disease Consultants of the Treasure Coast located in Sebastian, Mississippi."