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Partial Opioid Agonist

buprenorphine/naloxone oral product for Opioid Use Disorder (MATPharm Trial)

Phase 2 & 3
Waitlist Available
Led By Traci C Green, PhD, MSc
Research Sponsored by Lifespan
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 90 days post randomization
Awards & highlights

MATPharm Trial Summary

This trial will compare two methods of treating opioid addiction. One method involves medication and the other does not.

Eligible Conditions
  • Opioid Use Disorder

MATPharm Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 90 days post randomization
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 90 days post randomization for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Relapse to drug use
Retention in MAT
Secondary outcome measures
Emergency department visits
Hospitalizations
Primary care visits
Other outcome measures
Engagement in MAT

MATPharm Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Pharmacy MATExperimental Treatment4 Interventions
pharmacy-based medication assisted treatment for maintenance care of opioid use disorder
Group II: Usual careActive Control3 Interventions
usual medication assisted treatment for maintenance care of opioid use disorder
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Naltrexone
FDA approved
Naltrexone
FDA approved

Find a Location

Who is running the clinical trial?

University of Rhode IslandOTHER
52 Previous Clinical Trials
21,941 Total Patients Enrolled
The Miriam HospitalOTHER
238 Previous Clinical Trials
37,225 Total Patients Enrolled
LifespanLead Sponsor
40 Previous Clinical Trials
40,838 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Medication Maintenance Therapy in Community Pharmacy Settings
Traci Green 2019. "Medication Maintenance Therapy in Community Pharmacy Settings". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04139213.
All > Probuphine
~43 spots leftby Apr 2025
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