PXL-330 Platinum device for crosslinking with Peschke ribofflavin solution for Bacterial Keratitis
Study Summary
This trial is testing a new system to treat corneal thinning conditions to see if it is safe and effective.
- Keratoconus
- Bacterial Keratitis
- Unstable Keratoconus
Treatment Effectiveness
Effectiveness Progress
Study Objectives
1 Primary · 1 Secondary · Reporting Duration: 1 year
Trial Safety
Trial Design
2 Treatment Groups
Conventional
1 of 2
Pulsed, accelerated
1 of 2
Active Control
Experimental Treatment
300 Total Participants · 2 Treatment Groups
Primary Treatment: PXL-330 Platinum device for crosslinking with Peschke ribofflavin solution · No Placebo Group · Phase 1
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 10 - 45 · All Participants · 26 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Who else is applying?
What state do they live in?
| Missouri | 100.0% |
What site did they apply to?
| Pacific Clear Vision Institute | 100.0% |
What portion of applicants met pre-screening criteria?
| Met criteria | 100.0% |
Why did patients apply to this trial?
- "I have progressive KC in both eyes treated left in 2018 and needing treatment in right after condition worsening. Ideally help can keep me from further issues and help others dealing with my illness."
How many prior treatments have patients received?
| 1 | 100.0% |
Frequently Asked Questions
What are the potential risks associated with Peschke ribofflavin solution and PXL-330 Platinum device crosslinking?
"The safety of the PXL-330 Platinum device for crosslinking with Peschke ribofflavin solution is estimated at a 1 due to its Phase 1 clinical trial status; This indicates that only limited data exists in support of efficacy and safety." - Anonymous Online Contributor
How many participants are currently taking part in this medical experiment?
"Affirmative. According to the information posted on clinicaltrials.gov, this investigation is currently recruiting participants with an initial posting date of September 1st 2019 and a recent update occurring on September 14th 2021. In total, 300 patients are needed at one medical centre for the study's completion." - Anonymous Online Contributor
Does this trial include participants older than thirty years?
"According to the trial's stipulations, potential participants need to be between 10 and 45 years old." - Anonymous Online Contributor
Who is authorized to partake in this scientific experiment?
"This clinical trial is seeking 300 patients with keratoconus aged 10 to 45. To be eligible for the study, applicants must possess an unstable form of the condition." - Anonymous Online Contributor
Are there any vacancies for those interested in joining this experiment?
"Affirmative, according to clinicaltrials.gov this research study is still looking for participants. It was first advertised on September 1st 2019 and last updated two years later on September 14th 2021. 300 volunteers are needed from a single site." - Anonymous Online Contributor