Manipulation of spatiotemporal coordination during walking for Stroke
This study is evaluating whether a new approach to rehabilitation may help improve walking for individuals who have had a stroke.
See full descriptionAbout the trial for Stroke
Treatment Groups
This trial involves 2 different treatments. Manipulation Of Spatiotemporal Coordination During Walking is the primary treatment being studied. Participants will be divided into 2 treatment groups. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
Eligibility
This trial is for patients born any sex aged 18 and older. There are 8 eligibility criteria to participate in this trial as listed below.
Approximate Timelines
Measurement Requirements
This trial is evaluating whether Manipulation of spatiotemporal coordination during walking will improve 4 primary outcomes in patients with Stroke. Measurement will happen over the course of During study day two.
Who is running the study
Principal InvestigatorPatient Q & A Section
What are common treatments for stroke?
Treatment of a single stroke is uncommon and depends on the treatment of any underlying condition that may have contributed to the accident. Treatment of the patient also depends on the likelihood that the stroke will resolve itself without treatment.
How many people get stroke a year in the United States?
Rates of stroke vary in different cohorts depending on their age and gender. In people < or =65 years the rate is 2.3 per 1000 population while in men it is 3.5 per 1000 population. In women, the rate is 1.7 and 4.5 per 1000 population respectively.
What are the signs of stroke?
Brain lesions that result from a stroke can give rise to many signs and symptoms. The most common symptom is weakness; other symptoms include dizziness, numbness and trouble speaking. More than 50 different signs or symptoms can occur when stroke has occurred. Stroke can cause both temporary and permanent brain damage, and can result from a number of different causes. For more information about stroke risk factors and the signs and symptoms of stroke see the STROKE (STROke IscheMic [IS] stroke and tNSTEMI e[TRIAL] and [INTIMi]stroke Prevention Collaborative (SITS).\n
Can stroke be cured?
The evidence that some treatment interventions work is promising, but there are significant methodological problems related to blinding, randomisation, and attrition. Further research is required to establish effectiveness of some intervention and the optimum type and duration of intervention. The lack of clear differences in outcomes between the group having stroke unit care and the group having usual care care in the current research suggests that it may be inappropriate to equate intensive stroke unit care with 'usual care' stroke units.
What is stroke?
Stroke is a disease with a wide variety of cause, stroke is the 2nd leading cause of death in the United States in 2008. It is a stroke that can't be cured and it is a stroke that we can prevent. Prevention starts with identification and prompt treatment; treatment is the key to achieving the maximum benefit, therefore it is important to identify the risk factors in individuals. In the current era of evidence based care, stroke has the highest mortality of any neurological conditions. There are many treatments including standard and innovative medication, rehabilitation, and some invasive procedures, such as stenting procedures, bypass surgery, and surgical decompression from tumor, ruptured aneurysm, or hematoma.
What causes stroke?
The underlying causes of stroke can be divided into causes related to the blood--brain barrier, blood vessel stiffness and the blood clotting system. These causes may interact and have an effect on the other causes.
Has manipulation of spatiotemporal coordination during walking proven to be more effective than a placebo?
Findings from a recent study demonstrated an increase in the motor planning network for the walking and may facilitate movement recovery from neurorehabilitation. Moreover, it would be recommended that future research be directed toward clinical applications in chronic stroke patients.
Does manipulation of spatiotemporal coordination during walking improve quality of life for those with stroke?
There was no improvement in quality of life in patients who were systematically trained in spatiotemporal coordination during gait. In contrast, these patients who participated in intensive rehabilitation reported improvements in walking speed and a reduced level of dependency on a walker.
How does manipulation of spatiotemporal coordination during walking work?
The manipulation of the spatial structure of walking was not associated with more efficient spatiotemporal coordination during walking for patients with stroke, but it may be useful for patients with mild walking impairments under close supervision in the clinic.
Does stroke run in families?
There seem to be no strong familial clustering of ischemic stroke, but the risk of familial stroke is higher than is the general population. More data, particularly in other forms of stroke are needed to elucidate the underlying mechanism(s) of these associations.
What is the latest research for stroke?
Based on this data, there is growing evidence for the use of thrombolysis, thrombectomy and drug therapy for stroke. A variety of novel neuroprotective agents are being evaluated. Randomized trials are under way to assess different treatment strategies in acute stroke. The new and more efficient statin statin medications must be further investigated for treating atherosclerosis. Statins may be helpful in relieving symptoms of vasospasm after stroke. New and intriguing approaches in the treatment of strokes have been identified. The most promising of these are stroke prevention approaches. These include high-risk screening, early treatment of hypertension with medications such as ACE inhibitors, and treatment of hypertension after stroke with medications like anti-platelet agents.
Is manipulation of spatiotemporal coordination during walking safe for people?
These exploratory preliminary results suggest that individuals with good functional integrity, mobility, and balance could safely engage in a manipulation of spatial navigation skills during walking without fear of impaired walking performance. The manipulation of task-oriented movement of the pelvic girdle from an initial random walk pattern to a more optimal pattern appears to be safe, with or without the use of the LEMS in patients with chronic low back pain.