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low-BC Group for Cardiovascular Disease

Phase 1
Waitlist Available
Led By Ock K Chun, PhD
Research Sponsored by University of Connecticut
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up from baseline to 6 months
Awards & highlights

Study Summary

This trial looks at whether blackcurrant supplements can improve gut health, bone density, and heart health in adult women.

Eligible Conditions
  • Cardiovascular Disease
  • Osteoporosis
  • Gut Microbiome

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~from baseline to 6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and from baseline to 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Bone mineral density (BMD)
Secondary outcome measures
Gut microbiota profile
Other outcome measures
Blood pressure (SBP/DBP), BMI, WC, body composition
Concentrations of plasma IGF-1 and cGP
Concentrations of plasma IL-1β, IL-6, TNFα, Th17 and Treg
+3 more

Trial Design

3Treatment groups
Active Control
Placebo Group
Group I: low-BC GroupActive Control1 Intervention
consume: 1) one tablet containing 392 mg blackcurrant (BC) extract per capsule and 2) one calcium citrate caplet containing 400 mg calcium and 500 IU vitamin D
Group II: high-BC GroupActive Control1 Intervention
consume: 1) two capsules containing 392 mg BC extract per tablet (total 784 mg/day) and 2) one calcium citrate caplet containing 400 mg calcium and 500 IU vitamin D
Group III: Control GroupPlacebo Group1 Intervention
consume: 1) one placebo capsule and 2) one calcium citrate caplet containing 400 mg calcium and 500 IU vitamin D

Find a Location

Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

University of ConnecticutLead Sponsor
183 Previous Clinical Trials
158,119 Total Patients Enrolled
Ock K Chun, PhDPrincipal InvestigatorUniversity of Connecticut

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the patient population for this research limited to those below 40 years of age?

"The parameters for admission to this research project necessitate that applicants must be between 45 and 60 years old. For the under 18s, there are currently 43 studies available while those above 65 have access to 499 trials."

Answered by AI

Is enrollment still available for this experiment?

"According to clinicaltrials.gov, this particular study is not presently looking for participants; the first posting was made on July 20th 2021 and it has since been updated on August 29th 2022. However, there are 565 additional clinical trials which currently require enrolment from volunteers."

Answered by AI

What criteria must prospective participants fulfill in order to be considered for enrollment?

"This medical trial is recruiting 60 adults between the ages of 45 and 60 who suffer from cardiovascular diseases. Additionally, these participants must be physically active less than 7 hours per week, abstain from exercise 24 hours before blood or stool tests and 12 hours prior to bone measurements, avoid dietary supplements for the duration of the study, stay away from foods high in anthocyanins and fermented dairy products with viable Bifidobacteria or Lactobacilli bacteria strains, have not been taking hormone replacement therapy (HRT) for at least one year leading up to this study's initiation date, willing to ingest a daily berry concentrate supplement"

Answered by AI

What health hazards do people face if exposed to low-BC Group?

"Our team at Power concluded that the safety of low-BC Group is moderately high, scoring it a 1 on our risk scale. This reflects its status as a Phase 1 trial, with limited data backing up both efficacy and security concerns."

Answered by AI
~14 spots leftby Apr 2025