← Back to Search

Behavioural Intervention

Prehabilitation Exercise Program for Frailty

Phase 1

Waitlist Available

Led By Victor Ezeugwu, PhD

Research Sponsored by Victor Ezeugwu

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

50 years of age or older

Score of 4-6 (vulnerable, mildly or moderately frail) on the clinical frailty scale (CFS)

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 12 and 24 weeks

Awards & highlights

Study Summary

This trial studies whether prehabilitation (exercise/reducing sedentary behavior) can help reduce complications, hospital stays, and recovery times for people who are vulnerable or frail before surgery.

Who is the study for?

This trial is for people aged 50 or older who are scheduled for elective surgery and have been identified as vulnerable or mildly/moderately frail based on a clinical scale. They must be able to walk, with or without aids. Those with unstable medical conditions that limit exercise tolerance cannot participate.Check my eligibility

What is being tested?

The study tests if a pre-surgery program combining strength training exercises and activities aimed at reducing sitting time can decrease complications, shorten hospital stays, and speed up recovery in patients undergoing elective surgery.See study design

What are the potential side effects?

While the intervention focuses on exercise which typically has benefits like improved strength and mobility, potential side effects may include muscle soreness, fatigue, and an increased risk of falls or injury during the training period.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am 50 years old or older.

Select...

I am somewhat frail but not completely dependent on others for daily activities.

Select...

I am scheduled for a planned surgery.

Select...

I can walk by myself or with help like a cane or walker.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 12 and 24 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~12 and 24 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 and 24 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change from baseline gait speed at 12 and 24 weeks

Secondary outcome measures

Change from baseline Barthel Index at 12 and 24 weeks

Change from baseline Saint Louis University mental status (SLUMS) test

Change from baseline Timed-Up and Go (TUG) test at 12 and 24 weeks

+8 more

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: ExperimentalExperimental Treatment1 Intervention

Neuromuscular strength training: The experimental group will receive up to 24 sessions of neuromuscular strength training led by a physical therapist with expertise in geriatrics and movement behaviors. The program includes exercises such as pelvic lifts, lunges, step-ups, squats, and sit-stands. The difficulty level will progressively increase using techniques like manual resistance, dumbbells, and unstable surfaces. Sedentary behavior intervention: The experimental group will also undergo a sedentary behavior intervention based on social cognitive theory. It involves weekly coaching sessions to enhance self-efficacy in reducing sedentary time and increasing light-intensity activity throughout the day. Participants will be provided with a wrist-worn Fitbit activity monitor for daily feedback and to track adherence to the intervention. The aim is to encourage participants to "sit less and move more" throughout their waking hours.

Group II: Standard of careActive Control1 Intervention

The control group will receive standard of care that is provided as part of the perioperative surgical procedure and subsequent rehabilitation.

0 / 4Eligibility criteria met

Find a Location

Who is running the clinical trial?

Royal Alexandra HospitalOTHER

17 Previous Clinical Trials

7,878 Total Patients Enrolled

Victor EzeugwuLead Sponsor

Victor Ezeugwu, PhDPrincipal InvestigatorUniversity of Alberta

1 Previous Clinical Trials

50 Total Patients Enrolled

Media Library

Combined neuromuscular exercise training and 'sit less, move more' program (Behavioural Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT05977556 — Phase 1

Frailty Research Study Groups: Experimental, Standard of care

Frailty Clinical Trial 2023: Combined neuromuscular exercise training and 'sit less, move more' program Highlights & Side Effects. Trial Name: NCT05977556 — Phase 1

Combined neuromuscular exercise training and 'sit less, move more' program (Behavioural Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05977556 — Phase 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Has Experimental achieved authorization from the FDA?

"The risk profile for Experimental in this early-stage clinical trial is rated as a 1 due to the paucity of data validating its safety and efficacy."

Answered by AI

Are there any available vacancies for participants in this research trial?

"Reports on clinicaltrials.gov confirm that the medical trial, initiated on September 1st 2023, is not currently recruiting patients. However, there are 160 other studies seeking candidates at this time."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Perioperative Prehabilitation on Markers of Fitness and Frailty in Patients Undergoing Elective Surgery

Victor Ezeugwu 2026. "Perioperative Prehabilitation on Markers of Fitness and Frailty in Patients Undergoing Elective Surgery". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05977556.