CLINICAL TRIAL

Prehabilitation Program for Hernia, Ventral

Recruiting · 18+ · All Sexes · Stanford, CA

Effect of Prehabilitation on Surgical Outcomes of Abdominally-based Plastic Surgery Procedures

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About the trial for Hernia, Ventral

Eligible Conditions
Panniculus · Hernia, Ventral · Abdominoplasty · Flap Reconstruction · Ventral Hernias

Treatment Groups

This trial involves 2 different treatments. Prehabilitation Program is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Main TreatmentA portion of participants receive this new treatment to see if it outperforms the control.
Prehabilitation Program
BEHAVIORAL
Control TreatmentAnother portion of participants receive the standard treatment to act as a baseline.

About The Treatment

Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Prehabilitation Program
2018
Completed Early Phase 1
~100

Eligibility

This trial is for patients born any sex aged 18 and older. There is one eligibility criterion to participate in this trial as listed below.

Inclusion & Exclusion Checklist
Mark “yes” if the following statements are true for you:
- Adult patients (>18 years) who are undergoing elective abdominally-based plastic surgery operations in 3+ weeks by one of the following plastic surgeons: Nazerali, Lee, Murphy, Nguyen, Lorenz.
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Odds of Eligibility
Unknown<50%
Be sure to apply to 2-3 other trials, as you have a low likelihood of qualifying for this one.Apply To This Trial
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Approximate Timelines

Please note that timelines for treatment and screening will vary by patient
Screening: ~3 weeks
Treatment: varies
Reporting: Enrollment to time of surgery
Screening: ~3 weeks
Treatment: Varies
Reporting: Enrollment to time of surgery
This trial has approximate timelines as follows: 3 weeks for initial screening, variable treatment timelines, and reporting: Enrollment to time of surgery.
View detailed reporting requirements
Trial Expert
Connect with the researchersHop on a 15 minute call & ask questions about:
- What options you have available- The pros & cons of this trial
- Whether you're likely to qualify- What the enrollment process looks like

Measurement Requirements

This trial is evaluating whether Prehabilitation Program will improve 27 primary outcomes and 18 secondary outcomes in patients with Hernia, Ventral. Measurement will happen over the course of Enrollment to time of surgery.

Change from Baseline Potassium Levels at Time of Surgery
ENROLLMENT TO TIME OF SURGERY
Assessment for leukocytosis, anemia, renal disease; Part of Basic Metabolic Panel
ENROLLMENT TO TIME OF SURGERY
Change from Baseline Blood Urea Nitrogen Levels at Time of Surgery
ENROLLMENT TO TIME OF SURGERY
Assessment for leukocytosis, anemia, renal disease; Part of Basic Metabolic Panel
ENROLLMENT TO TIME OF SURGERY
Physical Function Test: 5-times-sit-to-stand test at 3 weeks
3 WEEKS
Will use the 5-times-sit-to-stand test. The 5-times-sit-to-stand test is a method to quantify functional lower extremity strength. Lower times indicate better scores.
3 WEEKS
Patient-Reported Outcome Measures: RAND 36-Item Health Survey (RAND-36) on Post-op day 30
POST-OPERATIVE DAY 30
Will use the RAND 36-Item Health Survey (RAND-36) to assess the patient's perceived health following their surgical procedure. The score for RAND-36 ranges from 0-100, having higher scores mean better outcomes.
POST-OPERATIVE DAY 30
Patient-Reported Outcome Measures: Abdominal Surgery Impact Scale (ASIS) on Post-op day 30
POST-OPERATIVE DAY 30
Will use the Abdominal Surgery Impact Scale (ASIS) to assess the patient's perceived health following their surgical procedure. The ASIS score ranges from 18-126, having higher scores indicate better quality of life.
POST-OPERATIVE DAY 30
Occurrence of surgical complications (Post-op day 180)
POST-OPERATIVE DAY 180
Will analyze the occurrence of surgical complications after surgery. Hematoma, seroma, or abscess.
POST-OPERATIVE DAY 180
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Who is running the study

Principal Investigator
C. B.
Cara Black, Resident Physician, PGY-1
Stanford University

Patient Q & A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What causes hernia, ventral?

It is suggested that this is a multifactorial condition. The following factors may play a part:\n1. genetic influences\n2. physical factors\n3. psychiatric factors\n4. congenital and developmental factors\n5. endocrine anomalies\n6. immune compromise\n7. genetic factors\n8. environmental triggers.\n9. no single model explanation can be used to describe all of the above factors, nor can they be considered wholly incompatible.

Anonymous Patient Answer

What are common treatments for hernia, ventral?

There are commonly used agents available in a variety of different forms. There is a dearth of comparative medical evidence and a paucity of evidence comparing the effects of agents. Trials have only been undertaken with the same agents to evaluate different adverse events. More studies are required before agents can be chosen on the basis of their putative benefits versus side effects.

Anonymous Patient Answer

How many people get hernia, ventral a year in the United States?

In a population sample of US adult women for each week of a year, rates of hernias, ventral and incisional, increase by 18 (Ventral), 12 (Incisional), and 7 (Hernia) per 10,000 adult women. There are high inter-week variations. This could be partly due to different age distributions, but probably relates more to an increased rate of incisional hernias in summer in some areas.

Anonymous Patient Answer

What is hernia, ventral?

A hernia is a protrusion of body tissue or organ through the weak wall of the abdominal cavity. It can come in different shapes, sizes and locations. Some common hernias are the umbilical hernia, inguinal hernia, chiasma hernia, and an inguinal hernia.\n

Anonymous Patient Answer

Can hernia, ventral be cured?

For patients with a ventral hernia, repair in the early years after the diagnosis of the illness is highly recommended. Recent findings shows that if repairs of ventral hernias are performed soon after the initial diagnosis of the illness, there is no significant difference in recurrence, incidence, or pain intensity between repairs performed in early and late repair periods.

Anonymous Patient Answer

What are the signs of hernia, ventral?

The following signs are observed in patients with a hernia, ventral: pain in the front part of the groin, a lump in the belly- or mid-frontal area, an unpleasant bowel movement, difficulty or incomplete passing stools or flatus. If the hernia, ventral is only diagnosed during laparotomy, the diagnosis is not clear. We suggest that a laparoscopy should be performed in patients with hernia, ventral symptoms or an unexplained weight loss.

Anonymous Patient Answer

Is prehabilitation program safe for people?

Prehabilitation is safe and beneficial for older persons when implemented in an appropriately structured program in the outpatient setting, with close surveillance by the surgeon.

Anonymous Patient Answer

What is the latest research for hernia, ventral?

This research shows a potential approach of overcoming hernia with new treatments, including gene therapies, stem cells and nanotechnology. Furthermore, this research shows a potential application of tissue engineering to the management of hernia repair. We hope all of these findings are useful to surgeons or patients for hernia treatments after the successful completion of this research.\n

Anonymous Patient Answer

Is prehabilitation program typically used in combination with any other treatments?

Overall, we found little evidence for the effectiveness of a prehabilitation program in combination with any other treatment for women with herniated discs of the lumbar spine. Although no conclusions from our analysis can be definitely drawn, these results may suggest to some clinicians that there is not much evidence to support the routine use of prehabilitation programs for this group of patients.

Anonymous Patient Answer

How serious can hernia, ventral be?

Findings from a recent study demonstrates the clinical significance of choosing an appropriate treatment in patients with hernia. Treatment needs to be individualized based on many factors, including the type of hernia repair, preoperative symptoms and general health, surgical technique, and outcome of the underlying cause(s).

Anonymous Patient Answer

What are the latest developments in prehabilitation program for therapeutic use?

The current study demonstrates an improved prehabilitation program by providing new information, as well as the possible usefulness of the exercise training, as a preventive model of recovery from the surgical treatment of abdominal hiatuses.

Anonymous Patient Answer

What is prehabilitation program?

Patients can learn how to perform specific activities before they are hospitalized, and in the future, they can join other prehab classes as their patient-physician relationship develops.

Anonymous Patient Answer
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