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Pemetrexed for Chordoma
Study Summary
This trial will test the safety and tolerability of pemetrexed in people with chordoma. Researchers will also collect data on side effects, tumor response, and biomarkers.
Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2012 Phase 3 trial • 256 Patients • NCT01005680Trial Design
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Who is running the clinical trial?
Frequently Asked Questions
Has something like this ever been attempted before?
"Since 2007, Genzyme (a Sanofi Company) has been investigating the efficacy of pemetrexed through clinical trials. After a trial involving 698 patients in 2007, it was approved for Phase 3 drug use and is currently being studied at 225 sites spanning 74 countries and 2395 cities."
How many individuals have registered for this medical experiment?
"Unfortunately, this trial has reached its recruitment capacity and is not looking for additional participants. It was initially announced on September 6th 2019 and last modified in August 5th 2022. However, 26 trials involving chordoma are enrolling patients while 225 studies related to Pemetrexed have open registration windows."
For what medical treatments is Pemetrexed commonly prescribed?
"Pemetrexed has been found to be efficacious in treating ovarian cancer as well as unresectable thymomas, mesotheliomas, and non-small cell lung cancers with a localised presentation."
Has Pemetrexed received endorsement from the FDA?
"The safety of Pemetrexed is estimated to be a 1 according to our team at Power, as this is just an initial trial with limited data regarding its efficacy and security."
Has Pemetrexed been explored in previous experiments?
"Currently, 225 clinical trials researching Pemetrexed have been launched. Of these, 87 are in the third phase of testing and 19466 locations around the world are conducting studies for this treatment. Winston-Salem in North carolina is hosting most of them."
Is this experiment currently open to recruitment?
"Unfortunately, this trial is not presently seeking candidates. First published on September 6th 2019 and updated most recently as of August 5th 2022, it is currently inactive. However, there are 26 trials with chordoma research still recruiting participants, in addition to 225 studies utilizing Pemetrexed that have active recruitment processes."
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