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Local Anesthetic

Numbing Agents for Hearing Loss

Q: What afflictions are commonly treated with Tetracaine?

Moderate and persistent cases of <a href="https://www.withpower.com/clinical-trials/psoriasis">psoriasis</a> can be managed with tetracaine. The medication may also prove to be beneficial for other ailments, including exanthema, mild throat inflammation, and minor burns.

Q: What is the current enrollment size for this clinical trial?

Affirmative. Clinicaltrials.gov cites that this medical trial is presently enrolling patients since its initial posting on 8/1/2021, with the latest update occurring on 9/20/2022. The study seeks 80 volunteers from a single location.

Q: Are there precedent studies that have utilized Tetracaine?

Currently, 5 clinical trials for Tetracaine are being conducted. One of these studies is in the third and final phase. The majority of testing sites are situated in Scottsdale, <a href="https://www.withpower.com/clinical-trials/arizona">Arizona</a>; however, there are also 4 other locations where this medication can be tested.

Q: Are there still opportunities for participants to join this experiment?

The information hosted on clinicaltrials.gov indicates that this trial is still recruiting patients, with the initial post posted on August 1st 2021 and the latest update being made September 20th 2022.

Phase < 1

Waitlist Available

Research Sponsored by Our Lady of the Lake Hospital

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up immediately following the procedure to 6 months from procedure

Awards & highlights

Study Summary

This trial is testing whether or not a numbing drop (tetracaine) is more effective and less painful than a numbing agent applied directly to the eardrum (phenol) for people getting a steroid injection into the ear for Meniere's disease or idiopathic sudden sensorineural hearing loss.

Who is the study for?

Adults over 18 with Meniere's disease or sudden sensorineural hearing loss who need intratympanic steroid injections can join. It's not for those under 18, pregnant women, prisoners, people unable to consent in writing, or anyone with a current eardrum perforation.Check my eligibility

What is being tested?

The trial is testing if Tetracaine drops are better than Phenol for numbing the ear during steroid injections. Patients will receive one of these anesthetics before their treatment to see which causes less pain and is more effective.See study design

What are the potential side effects?

Possible side effects include burning sensation upon application of phenol and potential persistent eardrum perforation. Side effects from tetracaine may include local discomfort or allergic reactions.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ immediately following the procedure to 6 months from procedure

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~immediately following the procedure to 6 months from procedure

This trial's timeline: 3 weeks for screening, Varies for treatment, and immediately following the procedure to 6 months from procedure for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Difference in Pain Score

Secondary outcome measures

Statistical difference in tympanic membrane perforation presence or absence after the steroid injection procedure when using either tetracaine or phenol as the local anesthetic

Trial Design

2Treatment groups

Active Control

Group I: TetracaineActive Control1 Intervention

Patients will be positioned in supine position at this time 0.5% tetracaine drops will be used to fill the ear canal. Tetracaine will then be allowed to stay in place for approximately 10 to 15 minutes with the patient's head positioned with affected ear up. After this, using an operative microscope the drops will be removed from the ear canal with suction.

Group II: PhenolActive Control1 Intervention

Patients will be positioned in supine position and tympanic membrane visualized with operative microscope. Phenol applicator will be used to topically apply 90% phenol to the injection site (posterior/Inferior aspect of tympanic membrane).

Do I qualify?Apply below to find out

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Who is running the clinical trial?

Our Lady of the Lake HospitalLead Sponsor

12 Previous Clinical Trials

759 Total Patients Enrolled

Louisiana State University Health Sciences Center - New OrleansUNKNOWN

1 Previous Clinical Trials

440 Total Patients Enrolled

Media Library

Tetracaine 5% drops (Local Anesthetic) Clinical Trial Eligibility Overview. Trial Name: NCT04794842 — Phase < 1

Intratympanic Steroid Injections Research Study Groups: Tetracaine, Phenol

Intratympanic Steroid Injections Clinical Trial 2023: Tetracaine 5% drops Highlights & Side Effects. Trial Name: NCT04794842 — Phase < 1

Tetracaine 5% drops (Local Anesthetic) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04794842 — Phase < 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What afflictions are commonly treated with Tetracaine?

"Moderate and persistent cases of psoriasis can be managed with tetracaine. The medication may also prove to be beneficial for other ailments, including exanthema, mild throat inflammation, and minor burns."

Answered by AI

What is the current enrollment size for this clinical trial?

"Affirmative. Clinicaltrials.gov cites that this medical trial is presently enrolling patients since its initial posting on 8/1/2021, with the latest update occurring on 9/20/2022. The study seeks 80 volunteers from a single location."

Answered by AI

Are there precedent studies that have utilized Tetracaine?

"Currently, 5 clinical trials for Tetracaine are being conducted. One of these studies is in the third and final phase. The majority of testing sites are situated in Scottsdale, Arizona; however, there are also 4 other locations where this medication can be tested."

Answered by AI

Are there still opportunities for participants to join this experiment?

"The information hosted on clinicaltrials.gov indicates that this trial is still recruiting patients, with the initial post posted on August 1st 2021 and the latest update being made September 20th 2022."

Answered by AI