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Local Anesthetic

Tetracaine Drops and Phenol for Hearing Loss

Our Lady of the Lake Hospital, Baton Rouge, LA
Targeting 3 different conditionsPhenol 90% concentration +1 morePhase < 1Waitlist AvailableResearch Sponsored by Our Lady of the Lake Hospital

Study Summary

This trial is testing whether or not a numbing drop (tetracaine) is more effective and less painful than a numbing agent applied directly to the eardrum (phenol) for people getting a steroid injection into the ear for Meniere's disease or idiopathic sudden sensorineural hearing loss.

Eligible Conditions
  • Intratympanic Steroid Injection
  • Sudden Sensorineural Hearing Loss
  • Meniere's Disease

Eligibility Criteria

Inclusion Criteria

You will be eligible if you check “Yes” for the criteria below
You must be 18 years old or older to participate.
You have been diagnosed with sudden hearing loss or Meniere's disease.
Your treatment plan involves getting a steroid injection in your ear.


Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~immediately following the procedure to 6 months from procedure
This trial's timeline: 3 weeks for screening, Varies for treatment, and immediately following the procedure to 6 months from procedure for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Difference in Pain Score
Secondary outcome measures
Statistical difference in tympanic membrane perforation presence or absence after the steroid injection procedure when using either tetracaine or phenol as the local anesthetic

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Active Control
Group I: TetracaineActive Control1 Intervention
Patients will be positioned in supine position at this time 0.5% tetracaine drops will be used to fill the ear canal. Tetracaine will then be allowed to stay in place for approximately 10 to 15 minutes with the patient's head positioned with affected ear up. After this, using an operative microscope the drops will be removed from the ear canal with suction.
Group II: PhenolActive Control1 Intervention
Patients will be positioned in supine position and tympanic membrane visualized with operative microscope. Phenol applicator will be used to topically apply 90% phenol to the injection site (posterior/Inferior aspect of tympanic membrane).

Find a Location

Who is running the clinical trial?

Our Lady of the Lake HospitalLead Sponsor
12 Previous Clinical Trials
759 Total Patients Enrolled
Louisiana State University Health Sciences Center - New OrleansUNKNOWN
1 Previous Clinical Trials
440 Total Patients Enrolled

Media Library

Tetracaine 5% drops (Local Anesthetic) Clinical Trial Eligibility Overview. Trial Name: NCT04794842 — Phase < 1
Intratympanic Steroid Injections Research Study Groups: Tetracaine, Phenol
Intratympanic Steroid Injections Clinical Trial 2023: Tetracaine 5% drops Highlights & Side Effects. Trial Name: NCT04794842 — Phase < 1
Tetracaine 5% drops (Local Anesthetic) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04794842 — Phase < 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What afflictions are commonly treated with Tetracaine?

"Moderate and persistent cases of psoriasis can be managed with tetracaine. The medication may also prove to be beneficial for other ailments, including exanthema, mild throat inflammation, and minor burns."

Answered by AI

What is the current enrollment size for this clinical trial?

"Affirmative. Clinicaltrials.gov cites that this medical trial is presently enrolling patients since its initial posting on 8/1/2021, with the latest update occurring on 9/20/2022. The study seeks 80 volunteers from a single location."

Answered by AI

Are there precedent studies that have utilized Tetracaine?

"Currently, 5 clinical trials for Tetracaine are being conducted. One of these studies is in the third and final phase. The majority of testing sites are situated in Scottsdale, Arizona; however, there are also 4 other locations where this medication can be tested."

Answered by AI

Are there still opportunities for participants to join this experiment?

"The information hosted on clinicaltrials.gov indicates that this trial is still recruiting patients, with the initial post posted on August 1st 2021 and the latest update being made September 20th 2022."

Answered by AI

Who else is applying?

What state do they live in?
What site did they apply to?
Our Lady of the Lake Hospital
What portion of applicants met pre-screening criteria?
Met criteria
How many prior treatments have patients received?

Why did patients apply to this trial?

How responsive is this trial?

Typically responds via
Average response time
  • < 2 Days
Most responsive sites:
  1. Our Lady of the Lake Hospital: < 48 hours
Recent research and studies
~0 spots leftby Dec 2023