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Lynparza for Breast Cancer

Phase < 1
Waitlist Available
Led By Jayanthi Lea, MD
Research Sponsored by University of Texas Southwestern Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up following 7 days of lynparza
Awards & highlights

Study Summary

This trial is testing a targeted therapy called Lynparza for 7 days to see if it's effective in treating ovarian and breast cancer. A tissue biopsy will be done before and after the treatment to see if there are any changes.

Eligible Conditions
  • Breast Cancer
  • Ovarian Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~following 7 days of lynparza
This trial's timeline: 3 weeks for screening, Varies for treatment, and following 7 days of lynparza for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Characterize changes in ADP ribosylation to PARP inhibition
Correlate DNA damage response to ADP ribosylated proteome
Ovulation Inhibition

Trial Design

1Treatment groups
Experimental Treatment
Group I: LynparzaExperimental Treatment1 Intervention
Lynparza taken orally at a dose of 300mg twice daily for 7 days
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Lynparza
2019
Completed Early Phase 1
~20

Find a Location

Who is running the clinical trial?

University of Texas Southwestern Medical CenterLead Sponsor
1,048 Previous Clinical Trials
1,053,721 Total Patients Enrolled
21 Trials studying Breast Cancer
6,212 Patients Enrolled for Breast Cancer
Jayanthi Lea, MDPrincipal InvestigatorUniversity of Texas Southwestern Medical Center
3 Previous Clinical Trials
42 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What qualifications must an individual possess in order to participate in this research?

"Applicants to this clinical investigation must be between 18 and 99 years old, suffering from breast cancer. A total of 14 participants are being sought out for the trial."

Answered by AI

Are new participants still being recruited for this project?

"Unfortunately, this clinical trial is no longer admitting patients. Initially posted on July 23rd 2019 and last updated March 22nd 2022, its recruitment period has come to an end. If you are still seeking participation opportunities, there are currently 2923 trials for breast cancer treatment and 188 studies involving Lynparza that remain open."

Answered by AI

Are individuals younger than 65 years old qualified for this clinical investigation?

"As per the specified inclusion criteria for this clinical study, prospective participants must be 18 years old or older and below 99."

Answered by AI

What therapeutic applications is Lynparza typically used for?

"Lynparza is commonly used for curative treatment and advanced directives. It has also been known to provide relief from several other medical issues such as malignant neoplasm of ovary, primary peritoneal cancer, hallucinations, somatic disorders."

Answered by AI

What other research initiatives have been launched utilizing Lynparza?

"Currently, Lynparza has 188 active clinical trials with 27 at Phase 3. Houston is the main location for these studies, but 9255 other sites are also participating in their assessment."

Answered by AI

What is the participation number for this experimentation?

"Unfortunately, this medical trial is not presently recruiting any new patients. It was initially posted in the summer of 2019 and last updated on March 22nd 2022. If you are seeking a different clinical study to join, there are currently 2923 trials involving breast cancer that are actively enrolling participants as well as 188 studies concerning Lynparza which have open spots for enrolment."

Answered by AI
~2 spots leftby Apr 2025