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Er:YAG Laser + Carbon Fiber Curette for Peri-Implantitis

Waitlist Available
Led By Robert Gyurko, DMD, PhD
Research Sponsored by Tufts University School of Dental Medicine
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Screening 3 weeks
Treatment Varies
Follow Up 3 days
Awards & highlights


The American Association of Oral and Maxillofacial Surgeons estimated that 69% of adults ages 35 to 44 have lost at least one permanent tooth. Dental implants have revolutionized dentistry by providing tooth-like replacement for missing teeth and a solution that is predictable with long-term success.. After the implant is placed, natural bacteria from the mouth can develop around implants just like around natural teeth. Studies have shown that bacterial contamination can cause peri-implantitis- gum disease or inflammation around the implant, eventually leading to bone loss. Removing bacteria from dental implant surfaces can prevent peri-implantitis, and surface debridement constitutes the basis of treatment of peri-implant disease. Typically, mechanical hand instrumentation using curettes to remove biofilm and calculus is the main basis for periodontal therapy. However, total debridement is difficult, and the hand tools may damage the surface of the implant and making it more plaque retentive. Studies have shown that mechanical non-surgical therapy alone is not sufficient to treat peri-implantitis. There is evidence that a dental laser may be an effective method to remove bacteria from implant surfaces, with less damage to the surface. One type of dental laser, Er:YAG, appears optimal for implant decontamination as the Er:YAG laser energy is primarily absorbed by water, resulting in vaporization of bacteria and minimal surface alterations on the implant surface.The aim of this study is to evaluate the efficiency of biofilm decontamination of Er:YAG laser compared to carbon fiber curette.


Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Percent Bacteria Biofilm

Trial Design

4Treatment groups
Experimental Treatment
Active Control
Group I: Er:YAG Laser + Carbon Fiber CuretteExperimental Treatment2 Interventions
Combination of Er:YAG Laser and carbon fiber curette
Group II: Er:YAG LaserExperimental Treatment1 Intervention
Er:YAG Laser only
Group III: No TreatmentActive Control1 Intervention
No treatment (control)
Group IV: Carbon Fiber CuretteActive Control1 Intervention
Carbon fiber curette only
First Studied
Drug Approval Stage
How many patients have taken this drug
Er:YAG Laser

Find a Location

Who is running the clinical trial?

Tufts University School of Dental MedicineLead Sponsor
6 Previous Clinical Trials
584 Total Patients Enrolled
Tufts UniversityLead Sponsor
268 Previous Clinical Trials
596,817 Total Patients Enrolled
Robert Gyurko, DMD, PhDPrincipal InvestigatorTUSDM
~1 spots leftby Jul 2025