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Procedure

Er:YAG Laser + Carbon Fiber Curette for Peri-Implantitis

N/A
Waitlist Available
Led By Robert Gyurko, DMD, PhD
Research Sponsored by Tufts University School of Dental Medicine
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 3 days
Awards & highlights

Study Summary

The American Association of Oral and Maxillofacial Surgeons estimated that 69% of adults ages 35 to 44 have lost at least one permanent tooth. Dental implants have revolutionized dentistry by providing tooth-like replacement for missing teeth and a solution that is predictable with long-term success.. After the implant is placed, natural bacteria from the mouth can develop around implants just like around natural teeth. Studies have shown that bacterial contamination can cause peri-implantitis- gum disease or inflammation around the implant, eventually leading to bone loss. Removing bacteria from dental implant surfaces can prevent peri-implantitis, and surface debridement constitutes the basis of treatment of peri-implant disease. Typically, mechanical hand instrumentation using curettes to remove biofilm and calculus is the main basis for periodontal therapy. However, total debridement is difficult, and the hand tools may damage the surface of the implant and making it more plaque retentive. Studies have shown that mechanical non-surgical therapy alone is not sufficient to treat peri-implantitis. There is evidence that a dental laser may be an effective method to remove bacteria from implant surfaces, with less damage to the surface. One type of dental laser, Er:YAG, appears optimal for implant decontamination as the Er:YAG laser energy is primarily absorbed by water, resulting in vaporization of bacteria and minimal surface alterations on the implant surface.The aim of this study is to evaluate the efficiency of biofilm decontamination of Er:YAG laser compared to carbon fiber curette.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Percent Bacteria Biofilm

Trial Design

4Treatment groups
Experimental Treatment
Active Control
Group I: Er:YAG Laser + Carbon Fiber CuretteExperimental Treatment2 Interventions
Combination of Er:YAG Laser and carbon fiber curette
Group II: Er:YAG LaserExperimental Treatment1 Intervention
Er:YAG Laser only
Group III: No TreatmentActive Control1 Intervention
No treatment (control)
Group IV: Carbon Fiber CuretteActive Control1 Intervention
Carbon fiber curette only
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Er:YAG Laser
2018
N/A
~70

Find a Location

Who is running the clinical trial?

Tufts University School of Dental MedicineLead Sponsor
6 Previous Clinical Trials
584 Total Patients Enrolled
Tufts UniversityLead Sponsor
265 Previous Clinical Trials
661,866 Total Patients Enrolled
Robert Gyurko, DMD, PhDPrincipal InvestigatorTUSDM

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who else is applying?

What state do they live in?
Georgia
Florida
Texas
Other
How old are they?
18 - 65
What site did they apply to?
Tufts University School of Dental Medicine
What portion of applicants met pre-screening criteria?
Did not meet criteria
Met criteria
How many prior treatments have patients received?
2
0

Why did patients apply to this trial?

I have tried many dentists to help with perimplantis but they cannot seem to help me so I am trying a clinical trial.
PatientReceived 1 prior treatment
I have a cracked bridge on my upper with 6 teeth on this bridge. I also have 10 of my own teeth on the bottom. I can hardly eat without pain!
PatientReceived 1 prior treatment

What questions have other patients asked about this trial?

How long will screening visits take?
PatientReceived 1 prior treatment

How responsive is this trial?

Typically responds via
Email
Most responsive sites:
  1. Tufts University School of Dental Medicine: < 24 hours
Average response time
  • < 1 Day
~1 spots leftby Apr 2025