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High Fat Diet (HFD) for Inflammation (LODI Trial)

N/A

Waitlist Available

Led By Sue Shapses, PhD

Research Sponsored by Rutgers, The State University of New Jersey

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up change from lfd (5 days) to hfd (5 days) over an average of 6 weeks

Awards & highlights

LODI Trial Summary

This trial will study the effect of high fat vs low fat diets on inflammation in older adults.

Eligible Conditions

Inflammation
Obesity
Dietary Fats

LODI Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline characteristics

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline characteristics

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline characteristics for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in Endotoxin from Low to High fat diet

Change in Microbiome composition

Secondary outcome measures

Endotoxin in response to a meal

Inflammatory markers

Lipopolysaccharide binding protein (LBP)

+2 more

Other outcome measures

Body composition in lean and obese weight groups

Change in CTX in response to a meal

Change in Glucose in response to a meal

+7 more

LODI Trial Design

2Treatment groups

Experimental Treatment

Group I: ObeseExperimental Treatment2 Interventions

BMI in Obesity range

Group II: Normal weight (lean)Experimental Treatment2 Interventions

Normal body weight

Do I qualify?Apply below to find out

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Who is running the clinical trial?

Rutgers, The State University of New JerseyLead Sponsor

429 Previous Clinical Trials

64,200 Total Patients Enrolled

3 Trials studying Inflammation

154 Patients Enrolled for Inflammation

Sue Shapses, PhDPrincipal InvestigatorRutgers, the State University

4 Previous Clinical Trials

233 Total Patients Enrolled

1 Trials studying Inflammation

18 Patients Enrolled for Inflammation

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What type of individuals are ideal candidates for this research experiment?

"This medical trial stipulates that 24 obese adults aged between 50 and 79 must be enrolled. The necessary prerequisites are: being of Men or Women gender, over 2 years postmenopausal if female; BMI ranging from 20-25 kg/m2 to 30-40 km/m2."

Answered by AI

What is the ultimate aim of this research?

"The primary end point of this experiment, which will be monitored between a Low Fat Diet (LFD) and High Fat Diet (HFD) over six weeks time frame is to measure any alteration in Lipopolysaccharide binding protein. Secondary goals encompass gauging the modifications in Interleukin-6, blood glucose response after consuming meals, and hsCRP levels."

Answered by AI

Are octogenarians welcome to participate in this investigation?

"This research is open to people aged 50-79 years old."

Answered by AI

Are there still vacancies in this experimental treatment program?

"Correct. According to the clinicaltrials.gov website, this medical research is actively searching for participants. It was initially posted on March 1st 2022 and updated most recently on October 25th 2022; it requires 24 patients from a single site to be recruited."

Answered by AI

What is the capacity of this research program?

"Correct. Clinicaltrials.gov verifies that this medical trial was first posted on March 1st 2022 and is currently actively seeking participants. 24 patients are required to be recruited from a single facility."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Lean and Obese: Dietary Inflammation

Sue A. Shapses, Ph.D., RD 2022. "Lean and Obese: Dietary Inflammation". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05327868.