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Negative Pressure Wound Therapy

Closed Incision Negative Pressure Therapy (ciNPT) for Arthritis (ENABLE Trial)

N/A
Waitlist Available
Led By Fred Cushner, MD
Research Sponsored by 3M
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up daily for 4 weeks post-surgery, then weekly for weeks 5-12
Awards & highlights

ENABLE Trial Summary

This trial will compare two methods of dressing wounds after surgery on both knees. One is the standard silver dressing, and the other is a closed incision negative pressure dressing. They will compare the amount of swelling in the legs after the surgery.

Eligible Conditions
  • Arthritis
  • Knee Arthritis
  • Surgical Wound
  • Leg swelling
  • Wounds and Injuries
  • Total Knee Replacement
  • Musculoskeletal Disorders

ENABLE Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~daily for 4 weeks post-surgery, then weekly for weeks 5-12
This trial's timeline: 3 weeks for screening, Varies for treatment, and daily for 4 weeks post-surgery, then weekly for weeks 5-12 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Secondary outcome measures
Average pain rating on 0-10 scale
Change in Knee Extension Angle
Change in Knee Flexion Angle
+6 more

ENABLE Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Closed Incision Negative Pressure Therapy (ciNPT) DressingExperimental Treatment1 Intervention
Prevena Restor Arthro-Form Dressing with Prevena Plus Therapy Unit
Group II: Standard Silver-containing DressingActive Control1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Closed Incision Negative Pressure Therapy (ciNPT)
2017
N/A
~300

Find a Location

Who is running the clinical trial?

3MLead Sponsor
157 Previous Clinical Trials
31,334 Total Patients Enrolled
KCI ManufacturingLead Sponsor
Fred Cushner, MDPrincipal InvestigatorHospital for Special Surgery, New York

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Evaluating Edema and Range of Motion Using Negative Pressure Therapy vs. Standard Surgical Dressing in Bilateral TKA
2020. "Evaluating Edema and Range of Motion Using Negative Pressure Therapy vs. Standard Surgical Dressing in Bilateral TKA". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04712019.
~2 spots leftby Apr 2025
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