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Behavioral Intervention

Gain-framed messaging plus NRT for Smoking Cessation

Phase 2
Waitlist Available
Led By Benjamin Toll, PhD
Research Sponsored by Medical University of South Carolina
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
50 years or older
at least a 20-pack year history of smoking
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 month follow-up
Awards & highlights

Study Summary

This trial is testing a new way to help lung cancer patients quit smoking, by framed messaging and nicotine replacement therapy. If successful, this study could help many people quit smoking.

Who is the study for?
This trial is for English-speaking individuals over 50 who currently smoke and have a significant smoking history. They must be willing to be randomly assigned to different treatments. People with recent heart issues, allergies to adhesives, unstable health conditions, or those already in tobacco treatment programs cannot join.Check my eligibility
What is being tested?
The study compares two approaches: gain-framed messaging plus Nicotine Replacement Therapy (NRT) versus standard unframed messages about quitting smoking. It's designed for lung cancer screening patients and aims to see which method helps them stop smoking more effectively.See study design
What are the potential side effects?
While the trial primarily focuses on messaging strategies, NRT can cause side effects like skin irritation from patches, sleep problems if used close to bedtime, headache, nausea, dizziness or racing heartbeat.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am 50 years old or older.
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I have smoked at least 20 packs of cigarettes a year.
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I am willing to be assigned to a treatment group by chance.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 month follow-up
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 month follow-up for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Secondary outcome measures
Smoking cessation rates

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: NRT plus Gain-framed MessagingExperimental Treatment1 Intervention
Gain-framed messaging plus NRT.
Group II: No NRT - Unframed MessagingActive Control1 Intervention
Unframed smoking cessation materials, but no NRT and no gain-framed messaging.

Find a Location

Who is running the clinical trial?

Medical University of South CarolinaLead Sponsor
931 Previous Clinical Trials
7,393,669 Total Patients Enrolled
National Cancer Institute (NCI)NIH
13,636 Previous Clinical Trials
40,929,182 Total Patients Enrolled
Benjamin Toll, PhDPrincipal InvestigatorMedical University of South Carolina
4 Previous Clinical Trials
663 Total Patients Enrolled

Media Library

Gain-framed messaging (Behavioral Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT03069924 — Phase 2
Smoking Cessation Research Study Groups: No NRT - Unframed Messaging, NRT plus Gain-framed Messaging
Smoking Cessation Clinical Trial 2023: Gain-framed messaging Highlights & Side Effects. Trial Name: NCT03069924 — Phase 2
Gain-framed messaging (Behavioral Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03069924 — Phase 2

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does the Food and Drug Administration recognize gain-framed messaging combined with nicotine replacement therapy as a legitimate treatment?

"The safety profile of Gain-framed messaging plus NRT was judged to be a 2 on the 1-3 scale, as this is a Phase 2 trial. This means that some data has been collected in regards to its safety, but nothing yet exists with regards to efficacy."

Answered by AI

Is there availability for participants in this trial?

"As indicated on clinicaltrials.gov, the trial is currently accepting patients and was initially posted in July 2017 with its most recent update taking place November 2022."

Answered by AI

What has been the outcome of previous experiments that incorporated both incentive-based messaging and nicotine replacement therapy?

"Initially examined in 2006 at the University of Hong Kong, gain-framed messaging plus NRT has been tested 396 times since. At present, 71 trials are running with a considerable number based out of Charleston, South carolina."

Answered by AI

How many participants are being treated through this trial?

"Affirmative. The clinicaltrials.gov platform indicates that this research trial is presently recruiting patients; the initial posting was on July 1st 2017 and it has been recently modified as of November 11th 2022. 367 participants are needed from two different medical centres to complete the study's requirements."

Answered by AI
~47 spots leftby Apr 2025