Gain-framed messaging plus NRT for Lung Cancer Screening

Phase-Based Progress Estimates
1
Effectiveness
2
Safety
Lung Cancer Screening+1 MoreGain-framed messaging plus NRT - CombinationProduct
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial is testing a new way to help lung cancer patients quit smoking, by framed messaging and nicotine replacement therapy. If successful, this study could help many people quit smoking.

Eligible Conditions
  • Lung Cancer Screening
  • Smoking Cessation

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

0 Primary · 1 Secondary · Reporting Duration: 6 month follow-up

6 month follow-up
Smoking cessation rates

Trial Safety

Safety Progress

2 of 3
This is further along than 68% of similar trials

Trial Design

6 Treatment Groups

No NRT - Unframed Messaging
1 of 6
No NRT - Messaging
1 of 6
No NRT - No Messaging
1 of 6
NRT - No Messaging
1 of 6
NRT plus Gain-framed Messaging
1 of 6
NRT plus Messaging
1 of 6

Active Control

Experimental Treatment

367 Total Participants · 6 Treatment Groups

Primary Treatment: Gain-framed messaging plus NRT · No Placebo Group · Phase 2

NRT plus Gain-framed Messaging
CombinationProduct
Experimental Group · 1 Intervention: Gain-framed messaging plus NRT · Intervention Types: CombinationProduct
NRT plus Messaging
CombinationProduct
Experimental Group · 1 Intervention: Gain-framed messaging plus NRT · Intervention Types: CombinationProduct
No NRT - Unframed Messaging
Behavioral
ActiveComparator Group · 1 Intervention: Unframed messaging materials · Intervention Types: Behavioral
No NRT - Messaging
Behavioral
ActiveComparator Group · 1 Intervention: Gain-framed messaging · Intervention Types: Behavioral
No NRT - No Messaging
Behavioral
ActiveComparator Group · 1 Intervention: Counseling alone · Intervention Types: Behavioral
NRT - No Messaging
Drug
ActiveComparator Group · 1 Intervention: Nicotine replacement therapy · Intervention Types: Drug

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 6 month follow-up

Who is running the clinical trial?

Medical University of South CarolinaLead Sponsor
838 Previous Clinical Trials
5,378,250 Total Patients Enrolled
National Cancer Institute (NCI)NIH
13,076 Previous Clinical Trials
41,139,181 Total Patients Enrolled
1 Trials studying Lung Cancer Screening
1,114 Patients Enrolled for Lung Cancer Screening
Benjamin Toll, PhDPrincipal InvestigatorMedical University of South Carolina
4 Previous Clinical Trials
663 Total Patients Enrolled
Alana Rojewski, PhDStudy DirectorMedical University of South Carolina
1 Previous Clinical Trials
80 Total Patients Enrolled

Eligibility Criteria

Age 18+ · All Participants · 5 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You have a pack-year history of smoking.
You are a current smoker.