← Back to Search

Virus Therapy

HCV Screening for Hepatitis C (DETECT HCV Trial)

N/A

Waitlist Available

Led By Jason Haukoos, MD, MSc

Research Sponsored by Denver Health and Hospital Authority

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 12 months following hcv diagnosis

Awards & highlights

DETECT HCV Trial Summary

This trial will compare two methods of screening for hepatitis C in emergency departments. One method screens everyone, while the other only screens people who are at risk.

Who is the study for?

This trial is for individuals who can consent to medical care, visit emergency departments during the study period, and are stable according to a nurse or doctor's assessment. It doesn't specify exclusions.Check my eligibility

What is being tested?

The DETECT HCV Screening Trial aims to compare two methods of hepatitis C screening in urban emergency departments: one that offers tests regardless of risk (nontargeted) and another that screens based on specific risk factors (targeted).See study design

What are the potential side effects?

Since this trial involves screening for Hepatitis C rather than treatment, there are no direct side effects from interventions like medications. However, participants may experience anxiety or stress from the testing process.

DETECT HCV Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 12 months following hcv diagnosis

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~12 months following hcv diagnosis

This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 months following hcv diagnosis for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Newly diagnosed active HCV

Secondary outcome measures

HCV test acceptance

HCV test completion

Other outcome measures

Completion of an evaluation by an HCV treatment expert

Completion of treatment with Direct-Acting Antivirals (DAAs)

Fibrosis staging

+3 more

DETECT HCV Trial Design

2Treatment groups

Experimental Treatment

Group I: Targeted ScreeningExperimental Treatment1 Intervention

The targeted HCV screening arm will consist of implementation of risk-based rapid opt-out HCV screening using current recommendations for HCV screening by the CDC, USPSTF, and AASLD-IDSA. Targeted HCV screening will consist of offering HCV testing to those identified with the following specific risk characteristics, adapted from the above recommendations: born between 1945 - 1965 ("birth cohort"); injection drug use (IDU); intranasal drug use;tattoo or piercing in an unregulated setting; or blood transfusion or organ recipient before 1992.

Group II: Nontargeted ScreeningExperimental Treatment1 Intervention

The nontargeted HCV screening arm will consist of implementing non-risk-based rapid opt-out HCV screening.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Alameda County Medical CenterOTHER

5 Previous Clinical Trials

77,065 Total Patients Enrolled

Johns Hopkins UniversityOTHER

2,259 Previous Clinical Trials

14,673,120 Total Patients Enrolled

18 Trials studying Hepatitis C

7,324 Patients Enrolled for Hepatitis C

Boston Medical CenterOTHER

382 Previous Clinical Trials

721,866 Total Patients Enrolled

3 Trials studying Hepatitis C

282 Patients Enrolled for Hepatitis C

Media Library

HCV Screening (Virus Therapy) Clinical Trial Eligibility Overview. Trial Name: NCT04003454 — N/A

Hepatitis C Research Study Groups: Nontargeted Screening, Targeted Screening

Hepatitis C Clinical Trial 2023: HCV Screening Highlights & Side Effects. Trial Name: NCT04003454 — N/A

HCV Screening (Virus Therapy) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04003454 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is there any availability for participants to join this clinical trial?

"Per the information listed on clinicaltrials.gov, this trial is not accepting new patients at present. It was initially posted in November of 2019 and last updated in May of 2023, although there are currently 283 other studies which are actively recruiting participants."

Answered by AI

Recent research and studies

TrialsJournal

The Determining Effective Testing in Emergency Departments and Care Coordination on Treatment Outcomes (DETECT) for Hepatitis C (hep C) Screening Trial: Rationale and Design of a Multi-center Pragmatic Randomized Clinical Trial of Hepatitis C Screening in Emergency Departments

Haukoos, Jason S., Sarah E. Rowan, James W. Galbraith, Richard E. Rothman, Yu-Hsiang Hsieh, Emily Hopkins, Rachel A. Houk, et al.. 2022. “The Determining Effective Testing in Emergency Departments and Care Coordination on Treatment Outcomes (DETECT) for Hepatitis C (hep C) Screening Trial: Rationale and Design of a Multi-center Pragmatic Randomized Clinical Trial of Hepatitis C Screening in Emergency Departments”. Trials. Springer Science and Business Media LLC. doi:10.1186/s13063-022-06265-1.

clinicaltrials.govStudy

The DETECT HCV Screening Trial

Jason Haukoos 2019. "The DETECT HCV Screening Trial". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04003454.