Autism-adapted Group Cognitive Behavioral Therapy for Suicidal Ideation

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Vanderbilt University Medical Center, Nashville, TN
Suicidal Ideation+4 More
Autism-adapted Group Cognitive Behavioral Therapy - Behavioral
Eligibility
< 18
All Sexes
What conditions do you have?
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Study Summary

Higher rates of depression are reported by autistic adolescents as compared to their non-autistic peers, which is problematic given adverse outcomes (e.g., negative self-esteem, lower academic performance) that are associated with depression. Despite the alarming rates of depression in autistic youth and associated safety concerns, few treatments have been developed. In this study, we investigate the feasibility, acceptability, and preliminary efficacy of an autism-adapted group cognitive-behavioral treatment for autistic adolescents (11-17 years old; middle and high school) in a pilot, nonrandomized trial. Specifically, we aim to increase adolescents' perception and understanding of self, including autistic identity, in order to treat depression. Intervention design and implementation were guided by autistic self-advocates and parents.

Eligible Conditions

  • Suicidal Ideation
  • Autism Spectrum Disorder
  • Depression
  • Self Esteem

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

2 Primary · 0 Secondary · Reporting Duration: Baseline to 6 months

Baseline to 6 months
Severity of adolescent depressive symptoms, parent-report
Severity of adolescent depressive symptoms, self-report

Trial Safety

Trial Design

1 Treatment Group

Autism-adapted Group Cognitive Behavioral Therapy
1 of 1
Experimental Treatment

32 Total Participants · 1 Treatment Group

Primary Treatment: Autism-adapted Group Cognitive Behavioral Therapy · No Placebo Group · N/A

Autism-adapted Group Cognitive Behavioral Therapy
Behavioral
Experimental Group · 1 Intervention: Autism-adapted Group Cognitive Behavioral Therapy · Intervention Types: Behavioral

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline to 6 months
Closest Location: Vanderbilt University Medical Center · Nashville, TN
Photo of vanderbilt university medical center 1Photo of vanderbilt university medical center 2Photo of vanderbilt university medical center 3
2006First Recorded Clinical Trial
3 TrialsResearching Suicidal Ideation
1026 CompletedClinical Trials

Who is running the clinical trial?

Vanderbilt University Medical CenterLead Sponsor
758 Previous Clinical Trials
590,055 Total Patients Enrolled
1 Trials studying Suicidal Ideation
200 Patients Enrolled for Suicidal Ideation
Jessica M Schwartzman, PhDPrincipal InvestigatorVanderbilt University Medical Center

Eligibility Criteria

Age < 18 · All Participants · 5 Total Inclusion Criteria

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About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.