Transcranial infrared laser stimulation for Manic Disorder

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Dell Medical School at the University of Texas, Austin, TX
Manic Disorder
Transcranial infrared laser stimulation - Device
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

Investigating the application of transcranial infrared laser stimulation in individuals with bipolar disorder.

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Manic Disorder

Study Objectives

5 Primary · 1 Secondary · Reporting Duration: PRE = ~ 1 week before first intervention verses POST after 6 weeks of intervention

Week 6
Changes in Composite Score of Cognitive Function
Week 6
Changes in Perfusion (Pre and Post Intervention)
Changes in Resting State fMRI (Pre and Post Intervention)
Changes in Resting State functional near-infrared spectroscopy (Pre and Post Intervention)
Changes in task-based fMRI (Pre and Post Intervention): cognitive task with emotional distractors
Week 6
Changes in task-based fMRI (Pre and Post Intervention): monetary reward and punishment

Trial Safety

Safety Progress

1 of 3

Other trials for Manic Disorder

Trial Design

1 Treatment Group

Intervention: Transcranial Infrared Laser Stimulation (TILS)
1 of 1
Experimental Treatment

36 Total Participants · 1 Treatment Group

Primary Treatment: Transcranial infrared laser stimulation · No Placebo Group · N/A

Intervention: Transcranial Infrared Laser Stimulation (TILS)
Device
Experimental Group · 1 Intervention: Transcranial infrared laser stimulation · Intervention Types: Device

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: pre = ~ 1 week before first intervention verses post after 6 weeks of intervention
Closest Location: Dell Medical School at the University of Texas · Austin, TX
Photo of Austin 1Photo of Austin 2Photo of Austin 3
N/AFirst Recorded Clinical Trial
0 TrialsResearching Manic Disorder
0 CompletedClinical Trials

Who is running the clinical trial?

Milken InstituteOTHER
6 Previous Clinical Trials
216 Total Patients Enrolled
Baszucki Brain Research FundUNKNOWN
3 Previous Clinical Trials
50 Total Patients Enrolled
University of Texas at AustinLead Sponsor
283 Previous Clinical Trials
67,205 Total Patients Enrolled

Eligibility Criteria

Age 18+ · All Participants · 8 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You have a primary diagnosis of Bipolar Disorder type 1 or 2, by structured clinical interview (SCID-5).
You are taking any standing psychotropics for 6 weeks.
You have a minimum dose of a benzodiazepine equivalent to 22.5 mg oxazepam or 7.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.