Your session is about to expire
← Back to Search
Behavioral Intervention
cognitive behavioral therapy for Bipolar Disorder
N/A
Waitlist Available
Led By David Miklowitz, PhD
Research Sponsored by University of California, Los Angeles
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
- Patient meets criteria for having experienced a (past or present) disorder marked by clinically significant mood instability, depression, and/or psychotic features (i.e., diagnosed with a mood disorder, adjustment disorder with depressed mood, or psychotic disorder) OR they are at clinical high risk for psychosis
Be younger than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 0 & 9 weeks, 6 months
Awards & highlights
Study Summary
This trial is comparing two different types of therapy to see which is more effective for young people at risk for mental disorders. The therapy involves learning skills and coping mechanisms, with the help of a mobile phone app.
Eligible Conditions
- Bipolar Disorder
- Parenting
- High Risk
- Mood Disorders
- Prodromal Symptoms
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 0 & 9 weeks, 6 months
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~0 & 9 weeks, 6 months
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Change from Baseline Children's Depression Rating Scale-Revised (CDRS-R; Poznanski & Mokros, 1996) scores at 9 weeks & 6 months.
Change from Baseline Children's Global Assessment Scale (C-GAS; Shaffer, 1983) scores at 9 weeks & 6 months
Change from Baseline Prodromal Questionnaire - Brief (PQ-B; Loewy, Pearson, Vinogradov, Bearden, & Cannon, 2011) scores at 9 weeks & 6 months
+2 moreSecondary outcome measures
Change from Baseline Brief COPE Inventory (Brief-COPE; Carver, 1997) scores at 9 weeks & 6 months
Change from Baseline Depression Anxiety Stress Scales-21 (DASS-21; Lovibond & Lovibond, 1995) scores at 9 weeks & 6 months
Change from Baseline Difficulties in Emotion Regulation Scale (DERS; Gratz & Roemer, 2004) scores at 9 weeks & 6 months
Trial Design
2Treatment groups
Experimental Treatment
Group I: Group MBCTExperimental Treatment1 Intervention
9 group sessions lasting 75-90 minutes each. The focus of sessions 1 through 4 will be learning to bring greater awareness to the present moment, on purpose, and nonjudgmentally. Appropriate responding is the focus of sessions 5 through 8. All skills are reviewed in session 9.
Group II: Group CBTExperimental Treatment1 Intervention
9 group sessions lasting 75-90 minutes each. CBT starts with psychoeducation about emotions, their primary functions, and how our emotions can affect the way we think and behave. They next learn about behavioral strategies that can help them manage or overcome difficult emotions. Group members also complete gradual exposure exercises, which involve engaging with activities that elicit negative emotions. Finally, group members are taught cognitive skills to help them cope with difficult/stressful thoughts.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
cognitive behavioral therapy
2010
Completed Phase 2
~930
mindfulness-based cognitive therapy
2020
N/A
~70
Find a Location
Who is running the clinical trial?
University of California, Los AngelesLead Sponsor
1,530 Previous Clinical Trials
10,264,642 Total Patients Enrolled
12 Trials studying Bipolar Disorder
948 Patients Enrolled for Bipolar Disorder
Danielle M. Denenny, PhDStudy DirectorUniversity of California, Los Angeles
Marc J. WeintraubStudy DirectorUniversity of California, San Diego
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Other Trials to Consider
Popular Categories
Share this study with friends
Copy Link
Messenger