Endovascular management for Aneurysm

Phase-Based Progress Estimates
University of Alberta Hospital, Edmonton, CanadaAneurysmEndovascular management - Procedure
All Sexes
What conditions do you have?

Study Summary

This trial is comparing two different ways to fix a burst brain aneurysm in people not previously included in a study.

Eligible Conditions
  • Ruptured Aneurysm

Treatment Effectiveness

Study Objectives

1 Primary · 6 Secondary · Reporting Duration: one year and five years

12 months
poor clinical outcome(mRS>2)
Month 12
Occurence of a "major" (saccular) aneurysm recurrence
Within a few hours (while awaiting treatment)
Occurence of aneurysm re-rupture following randomization but before treatment initiation
one year
Occurrence of an intracranial hemorrhage following treatment
one year and five years
Overall mortality and morbidity
Hour 48
Failure of aneurysm occlusion using the intended treatment modality
within a month or at discharge if earlier
Peri-treatment hospitalization lasting more than 20 days and/or discharge to a location other than home

Trial Safety

Trial Design

2 Treatment Groups

Endovascular management
1 of 2
Surgical management
1 of 2

Active Control

1724 Total Participants · 2 Treatment Groups

Primary Treatment: Endovascular management · No Placebo Group · N/A

Endovascular management
ActiveComparator Group · 1 Intervention: Endovascular management · Intervention Types: Procedure
Surgical management
ActiveComparator Group · 1 Intervention: surgical management · Intervention Types: Procedure

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: one year and five years

Who is running the clinical trial?

Centre hospitalier de l'Université de Montréal (CHUM)Lead Sponsor
329 Previous Clinical Trials
112,598 Total Patients Enrolled
14 Trials studying Aneurysm
4,342 Patients Enrolled for Aneurysm
Max Findlay, MDPrincipal InvestigatorUniversity of Alberta
Jean Raymond, MDPrincipal InvestigatorCentre hospitalier de l'Université de Montréal (CHUM)
9 Previous Clinical Trials
3,007 Total Patients Enrolled
6 Trials studying Aneurysm
1,525 Patients Enrolled for Aneurysm
Tim Darsaut, MDPrincipal InvestigatorUniversity of Alberta
2 Previous Clinical Trials
2,291 Total Patients Enrolled
2 Trials studying Aneurysm
2,291 Patients Enrolled for Aneurysm

Eligibility Criteria

Age 18+ · All Participants · 4 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You have a certain level of severity of subarachnoid hemorrhage, which is grade 4 or less.

Frequently Asked Questions

What is the size of this clinical research cohort?

"1724 qualified participants are necessary for this medical trial to be a success. Participants can join at numerous locations, including Montefiore Medical Center in Bronx, New York and Centre Hospitalier de l'Université de Montréal - Hôpital Notre Dame in Montreal, Quebec." - Anonymous Online Contributor

Unverified Answer

Are any individuals currently being enrolled into this research project?

"Correct. According to the information posted on clinicaltrials.gov, this medical study that was first published on November 12th 2012 is actively recruiting participants. 1724 patients need to be enrolled from 3 individual sites in order for the trial to be completed successfully." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.