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Text Messaging for Physical Inactivity in Middle Age (MASTERY Trial)

Phase 1
Waitlist Available
Led By Jeff C Huffman, MD
Research Sponsored by Massachusetts General Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 weeks; 12 weeks
Awards & highlights

Summary

This trial is testing whether a text message intervention can help middle-aged adults be more physically active. The intervention involves weekly text message sessions for 12 weeks.

Who is the study for?
This trial is for adults aged 45-64 who are not very active, doing less than 150 minutes of moderate to vigorous physical activity per week. They must be able to increase their physical activity and have a phone that can send texts. People with heart disease, mobility issues, or involvement in other well-being programs cannot join.Check my eligibility
What is being tested?
The study tests a text messaging program called MASTERY designed to boost physical activity over 12 weeks through weekly interactive texts about wellness activities, goal setting, and stress reduction techniques specific to midlife challenges.See study design
What are the potential side effects?
Since this intervention involves lifestyle changes rather than medication, side effects may include muscle soreness or fatigue due to increased physical activity. However, these are typically mild and decrease as fitness improves.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 weeks; 12 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 weeks; 12 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Moderate-Vigorous Physical Activity [MVPA]
Secondary outcome measures
Change in anxiety (Hospital Anxiety and Depression Scale anxiety subscale [HADS-A])
Change in blood pressure (millimeters of mercury)
Change in body mass index (in kilograms per square meter)
+21 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: MASTERY InterventionExperimental Treatment1 Intervention
Participants will complete a positive psychology activity, work towards a physical activity goal, and use a stress reduction technique, then will complete weekly text message sessions. In the first six weeks, participants will review the activities they performed the prior week, be introduced to new material, choose activities to perform that week, and set a new physical activity goal during the text message sessions. In the final 6 weeks, participants will review progress towards prior goals, set new physical activity goals, and choose positive psychology and stress reduction skills to use that week. Finally, over the course of the program participants will complete three brief calls with a study trainer to discuss progress.
Group II: Attentional controlActive Control1 Intervention
Participants will receive the same physical activity component noted in MASTERY along with added messages providing education and guidance about physical activity, from our past work. Control participants will not receive PP or midlife-related content.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
MASTERY
2019
N/A
~20

Find a Location

Who is running the clinical trial?

Massachusetts General HospitalLead Sponsor
2,955 Previous Clinical Trials
13,212,562 Total Patients Enrolled
Jeff C Huffman, MDPrincipal InvestigatorMassachusetts General Hospital
15 Previous Clinical Trials
1,067 Total Patients Enrolled

Media Library

MASTERY Clinical Trial Eligibility Overview. Trial Name: NCT04849052 — Phase 1
Middle Age Research Study Groups: Attentional control, MASTERY Intervention
Middle Age Clinical Trial 2023: MASTERY Highlights & Side Effects. Trial Name: NCT04849052 — Phase 1
MASTERY 2023 Treatment Timeline for Medical Study. Trial Name: NCT04849052 — Phase 1
~0 spots leftby Aug 2024
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