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P2Y12 Inhibitor

Cangrelor for Acute Coronary Syndrome (SWAP-6 Trial)

Phase 4
Waitlist Available
Led By Francesco Franchi, MD
Research Sponsored by University of Florida
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 4 hours
Awards & highlights

Summary

This trial is investigating whether there is a drug interaction when cangrelor and prasugrel are given together to patients undergoing coronary stenting.

Eligible Conditions
  • Acute Coronary Syndrome
  • Coronary Artery Disease

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~4 hours
This trial's timeline: 3 weeks for screening, Varies for treatment, and 4 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Platelet Reactivity Measured by VerifyNow

Side effects data

From 2018 Phase 4 trial • 50 Patients • NCT03247738
12%
minor bleeding
100%
80%
60%
40%
20%
0%
Study treatment Arm
Cangrelor
Placebo

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: Prasugrel + CangrelorExperimental Treatment2 Interventions
Cangrelor plus prasugrel concomitantly administered at the start of PCI
Group II: PrasugrelActive Control1 Intervention
Prasugrel only administered at the start of PCI
Group III: Cangrelor followed by PrasugrelActive Control2 Interventions
Cangrelor administered at the start of PCI plus prasugrel administered at the end of the cangrelor infusion
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Prasugrel
2013
Completed Phase 4
~24920
Cangrelor
2013
Completed Phase 4
~710

Find a Location

Who is running the clinical trial?

Scott R. MacKenzie FoundationOTHER
4 Previous Clinical Trials
147 Total Patients Enrolled
University of FloridaLead Sponsor
1,354 Previous Clinical Trials
712,987 Total Patients Enrolled
3 Trials studying Acute Coronary Syndrome
1,694 Patients Enrolled for Acute Coronary Syndrome
Francesco Franchi, MDPrincipal InvestigatorUniversity of Florida
5 Previous Clinical Trials
669 Total Patients Enrolled
~81 spots leftby Jul 2025
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