Intrathecal Morphine for morphine

Phase-Based Progress Estimates
3
Effectiveness
3
Safety
Medical University of South Carolina, Charleston, SC
morphine+3 More
Quadratus lumborum block - Drug
Eligibility
< 18
All Sexes
What conditions do you have?
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Study Summary

Patients between the ages of 12 months and 11 years who are undergoing ureteral reimplantation surgery will be randomized to receive intrathecal morphine, or bilateral quadratus lumborum block. The investigators will compare the effect that intrathecal morphine and quadratus lumborum blocks have on the duration of pain control as demonstrated by charted pain scores and morphine equivalents in the first 48 hours. This study will also assess the side effects of each intervention such as nausea and vomiting, and itching.

Eligible Conditions

  • morphine
  • Ureteral Reimplantation
  • Pediatrics
  • Pain

Treatment Effectiveness

Effectiveness Progress

3 of 3
This is further along than 93% of similar trials

Study Objectives

1 Primary · 3 Secondary · Reporting Duration: up to 48 hours post-operative

Hour 24
Duration of analgesia
Day 4
Total Length of PACU and Hospital Stay
Hour 48
Patient/Family Satisfaction
Side effects of each intervention

Trial Safety

Safety Progress

3 of 3
This is further along than 85% of similar trials

Trial Design

2 Treatment Groups

Intrathecal Morphine
1 of 2
quadratus lumborum block
1 of 2
Active Control

30 Total Participants · 2 Treatment Groups

Primary Treatment: Intrathecal Morphine · No Placebo Group · Phase 4

Intrathecal Morphine
Drug
ActiveComparator Group · 1 Intervention: Intrathecal Morphine · Intervention Types: Drug
quadratus lumborum block
Drug
ActiveComparator Group · 1 Intervention: Quadratus lumborum block · Intervention Types: Drug

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: up to 48 hours post-operative
Closest Location: Medical University of South Carolina · Charleston, SC
Photo of medical university of south carolina 1Photo of medical university of south carolina 2Photo of medical university of south carolina 3
1993First Recorded Clinical Trial
0 TrialsResearching morphine
1235 CompletedClinical Trials

Who is running the clinical trial?

Medical University of South CarolinaLead Sponsor
828 Previous Clinical Trials
5,371,823 Total Patients Enrolled
Natalie Barnett, MDPrincipal InvestigatorMedical University of South Carolina

Eligibility Criteria

Age < 18 · All Participants · 2 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You must be between the ages of 12 months and 11 years old.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.