← Back to Search

Insulin

Insulin for High Blood Sugar

Q: What is the current enrollment rate for this research endeavor?

The clinical trial is not recruiting presently. It was first posted on April 4th 2019 and the last update occurred August 16th, 2022. If you're interested in alternative studies, 69 research projects are actively accepting candidates with hyperglycemia while 72 trials require participants living with Insulin-related diseases.

Q: Has Insulin been previously examined in any clinical investigations?

Currently, there are 72 distinct studies on Insulin with 13 of them in their final stages. Most of these investigations take place near Orange, <a href="https://www.withpower.com/clinical-trials/california">California</a> but there are 248 other sites that have launched related clinical trials.

Q: Are there still open slots for participation in this investigation?

No longer actively recruiting, this trial was initially posted on April 4th 2019 and last updated August 16th 2022. Alternately, individuals with hyperglycemia can still explore 69 ongoing trials and those seeking Insulin treatments have 72 studies to consider for enrollment.

Phase < 1

Waitlist Available

Led By Smitha Pabbathi, MD

Research Sponsored by H. Lee Moffitt Cancer Center and Research Institute

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up during hospital admission, up to 30 days

Awards & highlights

Study Summary

This trial will compare the outcomes of cancer patients with high blood sugar who receive either the current standard of care for insulin administration or a new, individualized method.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ during hospital admission, up to 30 days

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~during hospital admission, up to 30 days

This trial's timeline: 3 weeks for screening, Varies for treatment, and during hospital admission, up to 30 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Blood Glucose

Secondary outcome measures

Duration of normal blood glucose level

Proportion of high blood glucose levels

Blood Glucose

Side effects data

From 2015 Phase 4 trial • 156 Patients • NCT02002221

13%

Nasopharyngitis

10%

Hyperhidrosis

Hunger

Tremor

Asthenia

Hypoglycaemia

Squamous cell carcinoma of the tongue

Femoral neck fracture

100%

80%

60%

40%

20%

Study treatment Arm

Vildagliptin (LAF237)

Placebo

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Basal-Prandial-Correctional Insulin RegimenExperimental Treatment1 Intervention

Participants hospitalized in the medical, hematologic, or bone marrow transplant units will begin with basal long-acting insulin glargine with correctional and prandial rapid-acting insulin that is personalized and precise, to achieve target blood glucose levels with daily assessments during hospitalization. Adjustments will be made in real time to reach the target range.

Group II: Standard of Care Insulin RegimenActive Control1 Intervention

Participants hospitalized in the medical, hematologic, or bone marrow transplant units' blood sugar levels will be managed with sliding scale insulin or a combination of long- and short-acting insulin as per standard of care.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Insulin

2000

Completed Phase 4

~4280

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

H. Lee Moffitt Cancer Center and Research InstituteLead Sponsor

543 Previous Clinical Trials

135,473 Total Patients Enrolled

Smitha Pabbathi, MDPrincipal InvestigatorMoffitt Cancer Center

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the current enrollment rate for this research endeavor?

"The clinical trial is not recruiting presently. It was first posted on April 4th 2019 and the last update occurred August 16th, 2022. If you're interested in alternative studies, 69 research projects are actively accepting candidates with hyperglycemia while 72 trials require participants living with Insulin-related diseases."

Answered by AI

Has Insulin been previously examined in any clinical investigations?

"Currently, there are 72 distinct studies on Insulin with 13 of them in their final stages. Most of these investigations take place near Orange, California but there are 248 other sites that have launched related clinical trials."

Answered by AI

Are there still open slots for participation in this investigation?

"No longer actively recruiting, this trial was initially posted on April 4th 2019 and last updated August 16th 2022. Alternately, individuals with hyperglycemia can still explore 69 ongoing trials and those seeking Insulin treatments have 72 studies to consider for enrollment."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Prospective Study of Personalized Approach to Inpatient Patients With Hyperglycemia

2019. "Prospective Study of Personalized Approach to Inpatient Patients With Hyperglycemia". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03904199.