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Saline

25% albumin for Complications of Liver Transplant

Phase 4
Waitlist Available
Led By Sheldon Magder, MD
Research Sponsored by McGill University Health Centre/Research Institute of the McGill University Health Centre
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 30 and 60 minutes after infusion
Awards & highlights

Study Summary

The primary aim of this study is to assess the effect of hyperoncotic albumin on vascular hemodynamics and oxygen delivery after orthotopic liver transplant. The secondary aim is to try to identify the dominant physiological mechanism so that we will be able to better identify patients that may benefit from the use of albumin (25%) boluses in addition to standard care in patients following liver transplantation.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~60 minutes after the infusion of the fluid
This trial's timeline: 3 weeks for screening, Varies for treatment, and 60 minutes after the infusion of the fluid for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Cardiac index (CI)
Secondary outcome measures
A decrease in leak and plasma expansion
Cardiac function response
Cardiac output response
+1 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: 25% albuminExperimental Treatment1 Intervention
Group II: SalineActive Control1 Intervention

Find a Location

Who is running the clinical trial?

McGill University Health Centre/Research Institute of the McGill University Health CentreLead Sponsor
442 Previous Clinical Trials
159,154 Total Patients Enrolled
Sheldon Magder, MDPrincipal InvestigatorMcGill University Health Centre/Research Institute of the McGill University Health Centre

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Effect of Hyperoncotic Albumin on Vascular Hemodynamics and Oxygen Delivery Following Orthotopic Liver Transplant
2011. "Effect of Hyperoncotic Albumin on Vascular Hemodynamics and Oxygen Delivery Following Orthotopic Liver Transplant". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01328132.
All > Liver Transplant
~1 spots leftby Apr 2025
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