← Back to Search

Transcranial Direct Current Stimulation

tDCS for Post-Stroke Neglect

N/A
Recruiting
Led By Emily S. Grattan, PhD OTR MS
Research Sponsored by VA Office of Research and Development
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Ischemic or hemorrhagic stroke 3 months post stroke
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up participants in the cross-sectional study will be assessed at baseline.
Awards & highlights

Study Summary

This trial will test a new intervention for post-stroke neglect, which combines repetitive task-specific practice with transcranial direct current stimulation. The goal is to establish a more comprehensive neglect measure.

Who is the study for?
This trial is for individuals who had a stroke at least 3 months ago and are experiencing unilateral neglect, with specific scores on the Virtual Reality Lateralized Attention Test and Fugl-Meyer Upper Extremity assessment. They must have inducible motor responses in their thumb muscles but cannot have severe spasticity, significant language or cognitive impairments, or any conditions that pose risks to MRI, TMS, or tDCS procedures.Check my eligibility
What is being tested?
The study is testing an innovative treatment combining repetitive task-specific practice with transcranial direct current stimulation (tDCS) to improve attention deficits after a stroke. Participants will be randomly assigned to receive either active tDCS or a sham (placebo) version alongside their exercises.See study design
What are the potential side effects?
Transcranial direct current stimulation may cause mild side effects such as itching, tingling, or discomfort at the electrode site. More serious risks include seizures; however these are rare. The sham procedure should not cause any side effects.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I had a stroke more than 3 months ago.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~participants will be assessed at baseline and 30 minutes later
This trial's timeline: 3 weeks for screening, Varies for treatment, and participants will be assessed at baseline and 30 minutes later for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in excitability of fronto-parietal connectivity
Secondary outcome measures
Change in upper extremity kinematics
Change on Behavioral Inattention Test
Other outcome measures
Behavioral Inattention Test
Catherine Bergego Scale
Naturalistic Action Test

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: Active tDCS plus RTPActive Control1 Intervention
Single session of bilateral active parietal cortex tDCS (2.0 mA for 30 minutes) paired with repetitive task-specific practice (RTP)
Group II: Sham tDCS plus RTPPlacebo Group1 Intervention
Single session of bilateral sham parietal cortex tDCS (for 30 minutes) paired with repetitive task-specific practice (RTP)

Find a Location

Who is running the clinical trial?

VA Office of Research and DevelopmentLead Sponsor
1,606 Previous Clinical Trials
3,305,988 Total Patients Enrolled
83 Trials studying Stroke
6,701 Patients Enrolled for Stroke
Emily S. Grattan, PhD OTR MSPrincipal InvestigatorRalph H. Johnson VA Medical Center, Charleston, SC
Emily S. Grattan, PhD MS BSPrincipal InvestigatorVA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA

Media Library

Active tDCS (Transcranial Direct Current Stimulation) Clinical Trial Eligibility Overview. Trial Name: NCT03317860 — N/A
Stroke Research Study Groups: Sham tDCS plus RTP, Active tDCS plus RTP
Stroke Clinical Trial 2023: Active tDCS Highlights & Side Effects. Trial Name: NCT03317860 — N/A
Active tDCS (Transcranial Direct Current Stimulation) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03317860 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the magnitude of patient participation in this trial?

"Affirmative. According to the information on clinicaltrials.gov, this medical trial is actively searching for participants. The study was first advertised in July 2018 and has been updated as recently as November 2022. Approximately 17 patients need to be recruited between 2 sites."

Answered by AI

Does this experiment currently have any open enrollment opportunities?

"Per the details provided on clinicaltrials.gov, this research is presently searching for volunteers- it was first posted in July 2nd 2018 and recently revised November 30th 2022."

Answered by AI
~1 spots leftby Sep 2024