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Long-Term Ocrelizumab for Multiple Sclerosis (OLERO Trial)
OLERO Trial Summary
This trial is for people who have gotten ocrelizumab in a previous study and are continuing treatment or in a follow-up phase.
OLERO Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowOLERO Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.OLERO Trial Design
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Who is running the clinical trial?
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- I am willing and able to follow the study's requirements.I was part of a Roche study (WA21092, WA21093, WA25046) and received or followed up after ocrelizumab treatment.
- Group 1: Ocrelizumab
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Pivotal Trial - The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What are the chances of negative side effects from Ocrelizumab?
"The available evidence suggests that Ocrelizumab is safe to use, so it received a score of 3."
How many different hospitals are testing this new medication?
"This trial is currently underway at 31 locations, including Hope Research Institute in Phoenix, MultiCare Health System Institute for Research and Innovation in Tacoma, and SUNY at Stony Brook in Stony Brook."
When will recruitment for this research project be completed?
"The sponsor, Hoffmann-La Roche, needs to recruit 1300 eligible patients from various locations, including Hope Research Institute in Phoenix, Arizona and MultiCare Health System Institute for Research and Innovation in Tacoma, Washington."
Are people still allowed to sign up for this experiment?
"Yes, this trial is still looking for participants. The information on clinicaltrials.gov shows that the trial was posted on 5/3/2022 and was last updated on 10/17/2022. They are looking for 1300 people to participate at 31 different locations."
Who else is applying?
What state do they live in?
What portion of applicants met pre-screening criteria?
How many prior treatments have patients received?
What site did they apply to?
Why did patients apply to this trial?
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