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GLP-1 Receptor Agonist
Exenatide for Parkinson's Disease
Phase 1
Waitlist Available
Led By David Vaillancourt, PhD
Research Sponsored by University of Florida
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline and one-year
Awards & highlights
Summary
This trial is testing Exenatide, a diabetes medication, to see if it can help people with Parkinson's Disease by improving their symptoms and slowing down the disease. The study focuses on people with Parkinson's because they might benefit from these potential effects. Exenatide may help the brain function better and protect brain cells, leading to better movement and slower disease progression. Exenatide has shown potential benefits in improving motor and non-motor symptoms in Parkinson's disease in previous studies.
Eligible Conditions
- Parkinson's Disease
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ baseline and one-year
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline and one-year
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Change in blood oxygen level-dependent(BOLD) signal in M1.
Change in blood oxygen level-dependent(BOLD) signal in the posterior putamen.
Change in blood oxygen level-dependent(BOLD) signal in the supplementary motor area(SMA).
+1 moreSide effects data
From 2017 Phase 4 trial • 8 Patients • NCT0205894038%
Death
100%
80%
60%
40%
20%
0%
Study treatment Arm
Exenatide
Trial Design
1Treatment groups
Experimental Treatment
Group I: ExenatideExperimental Treatment1 Intervention
This group will receive a weekly Exenatide 2mg injection for one year.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Exenatide
FDA approved
Find a Location
Who is running the clinical trial?
University of FloridaLead Sponsor
1,384 Previous Clinical Trials
762,582 Total Patients Enrolled
National Institute of Neurological Disorders and Stroke (NINDS)NIH
1,368 Previous Clinical Trials
652,250 Total Patients Enrolled
David Vaillancourt, PhDPrincipal InvestigatorUniversity of Florida
3 Previous Clinical Trials
51 Total Patients Enrolled
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