DBT-SG for Parasuicide

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
VA Connecticut Healthcare System West Haven Campus, West Haven, CT, West Haven, CT
Parasuicide+1 More
DBT-SG - Behavioral
Eligibility
18+
All Sexes
Eligible conditions
Select

Study Summary

This study is evaluating whether a group therapy can reduce suicide attempts in veterans.

See full description

Eligible Conditions

  • Parasuicide

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

This trial is evaluating whether DBT-SG will improve 1 primary outcome and 2 secondary outcomes in patients with Parasuicide. Measurement will happen over the course of Up to 18 month follow-up.

Month 18
Columbia-Suicide Severity Rating Scale
Coping
Up to18 month follow-up
Change in Emotion dysregulation

Trial Safety

Trial Design

2 Treatment Groups

VHA treatment as usual
1 of 2
DBT-SG plus VHA treatment as usual
1 of 2
Active Control
Experimental Treatment

This trial requires 300 total participants across 2 different treatment groups

This trial involves 2 different treatments. DBT-SG is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

DBT-SG plus VHA treatment as usualDialectical Behavior Therapy Skills Group (DBT-SG) in addition to VHA treatment as usual. Group is 24 weekly sessions teaching skills in emotion regulation, distress tolerance, interpersonal effectiveness, and mindfulness.
VHA treatment as usual
Behavioral
VHA treatment as usual for Veterans at risk for suicide attempt

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: up to18 month follow-up
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly up to18 month follow-up for reporting.

Closest Location

VA Connecticut Healthcare System West Haven Campus, West Haven, CT - West Haven, CT

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 7 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
The study team will need access to a telephone, video teleconference equipment, and a local facility if they are using remote procedures show original
The individual has had two or more suicide attempts in their lifetime, with one in the past six months, as measured by the Columbia-Suicide Severity Rating Scale (C-SSRS). show original
The participant is willing to provide contact information for someone who can help locate them if study staff are unable to contact them show original
Veterans who are eligible for VA health care can receive it at a participating site show original
current suicidal ideation (endorsing a suicidal ideation scale of at least 1 [passive ideation] on C-SSRS
that The text states that people can attend group sessions that provide support for quitting smoking. show original
The person had a high score on the emotion dysregulation scale. show original

Patient Q&A Section

What are the signs of parasuicide?

"The main signs of parasuicide include severe depression, suicidal thoughts and attempts and suicide. In order to minimise the extent of harm that suicides causes, it is important to intervene early in psychiatric patients with suicidal thoughts or urges." - Anonymous Online Contributor

Unverified Answer

Can parasuicide be cured?

"It is possible for parasuicide to regress and to be considered fully cured. If a parasuicide-related death occurs, the death is not a suicide but a homicide; and if the psychiatric disorder persists, it has to be treated." - Anonymous Online Contributor

Unverified Answer

How many people get parasuicide a year in the United States?

"Findings from a recent study estimates that there are 21 million women and 16 million men in the United States who experience suicide in their lifetime. Based on these estimates, it is expected that 18 million women and 5 million men die each year. In other words, 15–25% of all suicides in the United States are suicides by women. While this proportion may be less than one quarter in other countries, the fact does not detract from the enormous epidemiological and personal tragedy caused by suicide for all people. Preventing suicides is especially important for women." - Anonymous Online Contributor

Unverified Answer

What is parasuicide?

"The suicidal behavior should be closely monitored and analyzed through a thorough investigation. Parasuicide is defined as the deliberate or self-induced act of taking one's own life." - Anonymous Online Contributor

Unverified Answer

What causes parasuicide?

"There is very little information on the cause of the suicidal attack for men. The incidence of parasuicide was higher than that of homicide in this sample. In a recent study, findings suggest that socioeconomic status has an impact on the occurrence of suicidal attack among Taiwanese men and is a risk factor for suicide." - Anonymous Online Contributor

Unverified Answer

What are common treatments for parasuicide?

"Para-suicides are commonly treated with psychological counseling and psychotherapy, usually in combination with other medications, including antidepressants. There is no cure for parasuicides, so treatment is focused on symptom management and is highly dependent on the specific patient." - Anonymous Online Contributor

Unverified Answer

What does dbt-sg usually treat?

"We have described a very high frequency of treatment-resistant depression in our patient population. The fact that the patients with dbt-sg, a relatively new treatment, had similar rates of treatment- resistant depression as patients previously receiving other atypical antidepressants suggests that this agent may be useful in some patients with treatment-resistant depression." - Anonymous Online Contributor

Unverified Answer

How does dbt-sg work?

"Sg and Dbt-Dsg did not significantly affect the incidence of suicidal intent, attempt, or suicide among US men and women; neither did they affect the risk of suicide attempts and completions among women only. However, they did produce behavioral changes, including more frequent bouts of drunkenness. These data support the notion that Sg and Dbt-Dsg are unlikely to be effective treatments for suicidal behavior if their safety is not considered." - Anonymous Online Contributor

Unverified Answer

Is dbt-sg safe for people?

"Both the present study results and the results of earlier research suggest the need for studies with a longer follow-up time and larger study populations to make recommendations regarding the need to continue administering dbt-sg (to women of reproductive age) or discontinue administering it (to men)." - Anonymous Online Contributor

Unverified Answer

Have there been other clinical trials involving dbt-sg?

"dbt-sg can help to improve the quality of life in some patients, and it appears to improve the quality of life in patients who had a reduction in QALYs." - Anonymous Online Contributor

Unverified Answer

What is dbt-sg?

"The detection of dbt-sg from blood serum obtained 7 days after a suicide attempt does not indicate an increased risk of relapse. Therefore, we cannot conclude that people who had tried suicide are at higher risk of suicide compared to those of non-suicide attempters." - Anonymous Online Contributor

Unverified Answer

What are the latest developments in dbt-sg for therapeutic use?

"Despite the recent introduction of dbt-sg into the UK market in 2006, the safety and effectiveness of this drug still has to be clearly established before its use is recommended with people who have had an episode of BV. Additional studies are required in order to confirm the efficacy and safety of dbt-sg and provide insights on the optimal therapeutic regimen." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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