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Sublingual allergy immunotherapy tablet for Allergic Rhinitis (MATIC Trial)
MATIC Trial Summary
This trial is testing whether house dust mite tablets are better than a placebo at reducing allergy symptoms in children aged 5-11.
- Allergic Rhinitis due to House Dust Mite
- Dust Mite Allergy
MATIC Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.MATIC Trial Design
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Who is running the clinical trial?
Frequently Asked Questions
How many individuals are involved in this research project?
"This study is no longer recruiting patients. The listing for the clinical trial was first posted on October 12th, 2019 and edited for the last time on May 23rd, 2022. There are other active studies; as of right now, there 67 trials concerning allergic rhinitis and 2 more specifically for Sublingual allergy immunotherapy tablet admitting patients."
Are there any similar drugs that have undergone testing like Sublingual allergy immunotherapy tablet?
"There are two ongoing Phase 3 clinical trials for the Sublingual allergy immunotherapy tablet. Although most of the 145 live studies for this medication are based in Oklahoma City, Oklahoma, there is significant geographical diversity."
Has the Sublingual allergy immunotherapy tablet received FDA approval?
"Sublingual allergy immunotherapy tablet is rated a 3 for safety by our team at Power. This is because it has reached Phase 3 in clinical trials, meaning that there is both efficacy and safety data supporting its use."
If a potential patient is 35 years old or younger, can they be included in this research project?
"Children aged 5 to 11 can be enrolled in this clinical trial, as seen in the inclusion criteria. Out of the 72 total studies, 26 are for patients under 18 years old and 46 are for those over 65."
Are we currently able to enroll new patients in this trial?
"This study is not currently recruiting patients. However, if you're looking for other studies to participate in, there are 67 trials for allergic rhinitis and 2 Sublingual allergy immunotherapy tablet clinical trials that are actively enrolling participants."
Have patients undergone this type of treatment before as part of a clinical trial?
"Currently, there are 2 ongoing studies for Sublingual allergy immunotherapy tablet in 46 cities and 13 countries. The first clinical trial was conducted in 2018 and completed Phase 3 drug approval stages. ALK-Abelló A/S sponsored the study which enrolled 600 patients. Since then, 18293 similar trials have been run."
Are there a lot of research centers conducting this clinical trial in Canada?
"63 total sites are currently participating in this trial, with locations including North York, Marietta and Miami. If you are considering joining the trial, it may be helpful to select a site near you in order to reduce travel requirements."
How do I sign up for this opportunity to test a new medication?
"1459 children between the ages of 5 and 11 who struggle with allergic rhinitis are being recruited for this study. The most important candidate requirements are as follows: they must have had AR symptoms on 8 or more days in the 2 weeks leading up to the start of the study, be either male or female, have a history of HDM AR/C (with or without asthma), and still experience allergic rhinitis symptoms even after receiving allergy medication in the year prior to screening."
Who else is applying?
How old are they?
What portion of applicants met pre-screening criteria?
What state do they live in?
How many prior treatments have patients received?
Why did patients apply to this trial?
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