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Cannabinoid

Nabilone for Obesity

Phase 2
Waitlist Available
Led By Bernard Le Foll, MD, PhD
Research Sponsored by Centre for Addiction and Mental Health
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up blood drawn at baseline, week 5, week 9, and week 12
Awards & highlights

Study Summary

This trial is testing the safety and feasibility of administering nabilone, a cannabinoid drug similar to the active component of cannabis, to patients who are obese in order to determine if it is effective in reducing weight.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~blood drawn at baseline, week 5, week 9, and week 12
This trial's timeline: 3 weeks for screening, Varies for treatment, and blood drawn at baseline, week 5, week 9, and week 12 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Number of SAEs per treatment arm
Number of dropouts per treatment arm
Secondary outcome measures
Abdominal fat
Blood PYY levels
Blood cholesterol levels
+8 more

Trial Design

3Treatment groups
Experimental Treatment
Placebo Group
Group I: Low-Dose NabiloneExperimental Treatment1 Intervention
pms-nabilone titrated to 2 mg daily
Group II: High-Dose NabiloneExperimental Treatment1 Intervention
pms-nabilone titrated to 6 mg daily
Group III: PlaceboPlacebo Group1 Intervention
Placebo
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Nabilone
2014
Completed Phase 3
~730

Find a Location

Who is running the clinical trial?

Centre for Addiction and Mental HealthLead Sponsor
354 Previous Clinical Trials
81,096 Total Patients Enrolled
4 Trials studying Obesity
304 Patients Enrolled for Obesity
Bernard Le Foll, MD, PhDPrincipal InvestigatorCentre for Addiction and Mental Health
12 Previous Clinical Trials
338 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are patient registrations still open for this experiment?

"Affirmative. According to the clinicaltrials.gov database, this medical trial is presently recruiting patients that it first posted on September 17th 2021 and last updated on March 7th 2022. The study seeks 60 participants from a single site location."

Answered by AI

Do we have a comprehensive understanding of the uses and effects of Nabilone from past research?

"Currently, there are 5 active trials looking into the efficacy of Nabilone. Of those studies, 3 have reached Phase 3 status. The majority of research is based in Toronto but 8 clinical sites across Canada are running these experiments."

Answered by AI

Can I enroll in the present clinical trial?

"For those aged between 25 and 45, this trial is seeking 60 candidates with obesity (BMI > 30 kg/m2). If they wish to partake in the imaging component of the study, applicants must not exceed 315 lbs or 166.6 cm circumference at its widest point."

Answered by AI

Is Nabilone a reliable therapeutic option with few adverse effects?

"Due to lack of efficacy evidence, our team at Power judged Nabilone's safety on a scale from 1 to 3 and gave it a 2."

Answered by AI

What is the size of the cohort participating in this experiment?

"Affirmative. According to clinicaltrials.gov, this research trial is actively seeking participants following its initial posting on September 17th 2021 and most recent edit on March 7th 2022. The recruitment goal for the study is 60 patients from one medical facility."

Answered by AI

Is there an age restriction on participation in this experiment?

"As per the prerequisites for this medical study, participants must be aged between 25 and 45."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
A Pilot Trial of Nabilone for the Treatment of Obesity
2021. "A Pilot Trial of Nabilone for the Treatment of Obesity". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04801641.
~7 spots leftby Apr 2025
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