← Back to Search

Other

PL9643 Opthalmic Solution for Dry Eye Syndrome (MELODY-1 Trial)

Phase 3
Waitlist Available
Research Sponsored by Palatin Technologies, Inc
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline and week 12 (day 85)
Awards & highlights

Summary

This trial is testing PL9643 eye drops to see if they can safely and effectively treat dry eyes. Patients with dry eyes will use these drops regularly over a few months. The drops are expected to help keep the eyes moist and reduce discomfort.

Eligible Conditions
  • Dry Eye Syndrome

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline and week 12 (day 85)
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline and week 12 (day 85) for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Conjunctival Sum Lissamine Green Staining
Inferior Corneal Fluorescein Staining
Ocular Discomfort

Side effects data

From 2014 Phase 4 trial • 40 Patients • NCT01602692
40%
Nausea
10%
Vomiting
100%
80%
60%
40%
20%
0%
Study treatment Arm
Tumescent Solution With Dilute Epinephrine
Tumescent Solution With Dilute Lidocaine and Epinephrine

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: PL9643 Opthalmic SolutionExperimental Treatment1 Intervention
PL9643 ophthalmic solution bilaterally three times a day.
Group II: Vehicle Opthalmic SolutionActive Control1 Intervention
Vehicle opthalmic solution bilaterally three times a day.

Find a Location

Who is running the clinical trial?

Palatin Technologies, IncLead Sponsor
11 Previous Clinical Trials
2,418 Total Patients Enrolled
Jason WintersStudy DirectorPalatin
~64 spots leftby Oct 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top