Adductor Canal Block for Pain, Postoperative

Phase-Based Progress Estimates
2
Effectiveness
3
Safety
Loyola University Medical Center, Maywood, IL
Pain, Postoperative+2 More
Adductor Canal Block - Drug
Eligibility
18+
All Sexes
What conditions do you have?
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Study Summary

This study is evaluating whether one of two pain reducing techniques is better than the other.

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Eligible Conditions

  • Pain, Postoperative
  • Post-Operative Pain, Chronic

Treatment Effectiveness

Effectiveness Progress

2 of 3
This is further along than 85% of similar trials

Study Objectives

This trial is evaluating whether Adductor Canal Block will improve 3 primary outcomes in patients with Pain, Postoperative. Measurement will happen over the course of During post-surgical hospitalization.

Hour 48
Analgesic efficacy
During post-surgical hospitalization
Rescue narcotics use
Total narcotic consumption

Trial Safety

Safety Progress

3 of 3
This is further along than 85% of similar trials

Trial Design

2 Treatment Groups

Group B
1 of 2
Group A
1 of 2
Active Control
Experimental Treatment

This trial requires 100 total participants across 2 different treatment groups

This trial involves 2 different treatments. Adductor Canal Block is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are in Phase 3 and have had some early promising results.

Group A
Drug
Group A patients will receive their treatment at the completion of the case while under general anesthesia. The anesthesia provider will identify the adductor canal using ultrasound guidance and inject 15ccs of 0.5% marcaine with epinephrine around the saphenous nerve. Group A patients will receive placebo intra-articular and arthroscopic portal site saline injections equal in volume and procedure time point as the treatment in Group B. At the completion of the case, the patient will be extubated and transferred to the PACU.
Group B
Drug
Group B will receive 20ccs of 2% lidocaine with epinephrine as an intra-articular injection. At the completion of the arthroscopic procedure the patient will receive an additional 20ccs of 0.5% marcaine with epinephrine intra-articular injection. Group B patients will also receive 10ccs of 2% lidocaine with epinephrine injected superficially into each of the arthroscopic portal sites. Group B patients will receive a 15cc saline injection around the saphenous nerve under the same procedure as the adductor canal block for Group A. At the completion of the case, the patient will be extubated and transferred to the PACU.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Adductor Canal Block
2019
Completed Phase 4
~600

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 1, 2, 4, 8, 12, 24, 36, and 48 hours after surgery
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 1, 2, 4, 8, 12, 24, 36, and 48 hours after surgery for reporting.

Closest Location

Loyola University Medical Center - Maywood, IL

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 2 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
ASA I-III patients
Age 18 to 65 years

Patient Q&A Section

How many people get pain, postoperative a year in the United States?

"Around 600,000 Americans received a surgical surgical procedure and experienced pain during the first postoperative month. About half of the individuals who experienced pain thereafter received a narcotic. The study findings suggest that nearly half of American adults will receive a narcotic post-treatment." - Anonymous Online Contributor

Unverified Answer

What are the signs of pain, postoperative?

"We summarize this information herein.\n\nPhysical exam:\n\nThe most common cause of pain in adults is bone or joint pain. Joint pain is the most common cause of pain in children." - Anonymous Online Contributor

Unverified Answer

What causes pain, postoperative?

"Pregnant women experience pain following childbirth; many of these women will go on to undergo further maternity care (e.g. postnatal care) and may be prescribed pain medication. Pain following childbirth is a major global problem with substantial social and socio-economic impacts. Pregnant women should be offered the opportunity of effective palliative care in terms of pain management, palliative care, and quality of care." - Anonymous Online Contributor

Unverified Answer

What are common treatments for pain, postoperative?

"Results from a recent paper, the most commonly used medications for pain were: standard non-steroidal anti-inflammatory drugs (NSAIDs) and opioids. In addition to these, some patients were prescribed other medications, including anticonvulsants and mood stabilizers.\n" - Anonymous Online Contributor

Unverified Answer

What is pain, postoperative?

"Nearly half of those in the postoperative category reported severe postoperative pain as compared with 9% of the general population. These data indicate that appropriate pain control for hospitalized patients is necessary." - Anonymous Online Contributor

Unverified Answer

Can pain, postoperative be cured?

"The study suggests that pain can be a treatment for pain but that this need not be the only way forward from a positive to a negative perception." - Anonymous Online Contributor

Unverified Answer

Does adductor canal block improve quality of life for those with pain, postoperative?

"The block was not found to affect the quality of life questionnaires in the present study. Results from a recent clinical trial, there was a non-significant trend towards better quality of life in those receiving block injections. Further trials are required to confirm these results." - Anonymous Online Contributor

Unverified Answer

How serious can pain, postoperative be?

"The severity of postoperative pain can vary widely. The impact of moderate postoperative pain was greatest when patients had an additional medical or surgical issue, experienced pain flares within a hospital, or were receiving analgesic pain medication." - Anonymous Online Contributor

Unverified Answer

What are the common side effects of adductor canal block?

"The most common side effects were pain and hypotension. A single injection with a needle-in-guiding guide catheter in the adductor canal achieves good adduction by injecting medication directly into the lumbosacral plexus." - Anonymous Online Contributor

Unverified Answer

What is adductor canal block?

"A systematic review of the literature demonstrates that the current available evidence favors the use of HAACB for surgical treatment of sciatica. The available evidence is in agreement with NICE guidelines in recommending HAACB as an acceptable treatment option for this condition." - Anonymous Online Contributor

Unverified Answer

Have there been any new discoveries for treating pain, postoperative?

"For relieving pain in patients after knee or hip joint operation, there are several options, such as a number of local pain interventions, local and general epidural analgesics and general anesthetics. The use of selective serotonin reuptake inhibitor and tricyclic antidepressant is another option." - Anonymous Online Contributor

Unverified Answer

Does pain, postoperative run in families?

"Findings from a recent study suggest an increased incidence of pain and run in pain families and suggests the value of a detailed, thorough history and assessment by an anesthesia provider." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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