Treatment for Breast Cancer
This study is evaluating whether a combination of chemotherapy and microwave thermotherapy is more effective than chemotherapy alone in treating women with locally advanced breast cancer.
See full descriptionAbout the trial for Breast Cancer
Treatment Groups
This trial involves a single treatment. Treatment is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are in Phase 2 and have already been tested with other people.
Eligibility
This trial is for female patients aged 18 and older. There are 10 eligibility criteria to participate in this trial as listed below.
Approximate Timelines
Patient Q & A Section
What are common treatments for breast cancer?
A number of [breast cancer](https://www.withpower.com/clinical-trials/breast-cancer) treatments are used, but the data are typically not detailed. The treatment depends on the type of cancer and how advanced it is, so some treatments may not be appropriate for all tumours. Common options include surgery, chemotherapy, radiotherapy, targeted therapy, and a combination of these.
What causes breast cancer?
The cause of [breast cancer](https://www.withpower.com/clinical-trials/breast-cancer) is complex. It is now being more and more determined that the environment of the breast influences breast cancer, and in particular, the level and type of exposures.
What is breast cancer?
Breast cancer is one of the most dangerous forms of cancer, and the leading cause of death in women worldwide. The most effective treatment for [breast cancer](https://www.withpower.com/clinical-trials/breast-cancer) is to treat the disease before it begins to spread, to surgery that removes the tumor as much as possible. Cancer of the breast is usually an advanced disease that usually does not react to chemotherapy or radiation treatment.
Can breast cancer be cured?
Although there is only a modest reduction in [breast cancer](https://www.withpower.com/clinical-trials/breast-cancer) recurrence (approximately 17%) after mastectomy if treatment to cure is undertaken earlier than cancer-associated bone metastasis, mammography screening can reduce breast cancer mortality, the primary cause of death, by 25%; this is mainly because of earlier detection as no improvement in treatment in the prevention of recurrence has been shown. Breast cancer cannot therefore be cured.
How many people get breast cancer a year in the United States?
Among the sample, women who had mammograms and did not have other screening examinations were more likely to be at increased risk of breast cancer than those who did not have mammograms; this result did not persist when controlling for other known risk factors for breast cancer. Screening mammography is likely to have a significant preventive effect on breast cancer.
What are the signs of breast cancer?
As breast cancer can present in a variety of ways, identification of the signs and symptoms of breast cancer is imperative for improving diagnosis of this tumour. Symptoms such as unexplained pain, redness, swelling, or nipple discharge with or without skin changes suggest breast cancer.
What is the average age someone gets breast cancer?
There is a clear disparity between younger and older women’s rates of diagnosis, however, the age at diagnosis is not associated with prognosis or stage in either ER/PR-positive or [triple negative breast cancer](https://www.withpower.com/clinical-trials/triple-negative-breast-cancer). In this population-based cohort of women aged 45-79 years presenting for an initial biopsy, age is not a predictor of survival from breast cancer. In a recent study, findings suggest that early screening or the benefits of aggressive treatment for younger women may be outweighed by the side effects of such intervention.
How quickly does breast cancer spread?
Most tumors grow rapidly and therefore, even in a relatively small mass, a curative treatment and careful follow up are needed. Also, most people with breast cancer were not aware of the fact that their initial tumor was the same as that of somebody else.
Have there been other clinical trials involving treatment?
There are several trials under way or already completed, like the ones mentioned in the next paragraph. There is no data available for the others. If any of them has a favorable result, it certainly would alter the current paradigm of the use of surgery as the sole treatment option for women with DCIS.
How does treatment work?
Findings from a recent study has led to the identification of a need for the need for greater information about treatment options, and of interest to oncologists, patients and their carers. The information provided in this study is useful in improving this gap.
What is treatment?
Patients who receive surgery to control cancer are more likely to be cured than those who do not. Patients with metastatic disease are more likely to have longer survival than those with localized disease. A cure is the most common hope for surgery and chemotherapy after diagnosis with breast cancer. Most patients do not survive 5 years after diagnosis, but long-term survival is possible if all disease is removed surgically, chemotherapy is successful, and a second-line agent is used after chemotherapy failure. Although it always seems to be a fight, many patients win and endure an extraordinary battle. Treatment of both the primary tumor and localized or metastatic disease after a diagnosis of breast cancer can improve survival.
What are the common side effects of treatment?
The side effects are usually very mild and disappear in less than a month after commencing treatment with Aprepitant. Most side effects are similar to those seen in the breast cancer population and include nausea/vomiting, fatigue, malaise/muscle aches, and swelling/edema. Other common side effects include headache/migraine, and sinusitis. Rarely, severe allergic reactions to the antifungal agent occur, but in many cases these may be the first signs of a serious allergy. This happens, for example, when the patient develops skin rash/urticaria that is not alleviated with antihistamines.