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Nutritional Supplement

Egg/Plant-Based Food Pairing for Nutritional Requirements

N/A
Waitlist Available
Research Sponsored by Ohio State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 0, 3, 4.5, 6, 7.5, 9, 12, 24, 36, 48, 72 hours post-ingestion of spinach
Awards & highlights

Study Summary

This trial is testing whether eggs can help improve the nutrient absorption of vitamins E and K from plant foods.

Who is the study for?
This trial is for healthy adults with normal blood sugar, cholesterol levels, and body weight. Participants should not have gastrointestinal disorders or be taking medications that affect lipid or glucose metabolism. Smokers, vegetarians, pregnant women, heavy drinkers, those who changed their weight significantly recently or exercise extensively are excluded.Check my eligibility
What is being tested?
The study tests if eating eggs along with deuterium-labeled spinach increases the body's absorption of vitamins E and K from the spinach compared to eating spinach alone or with vegetable oil. It will measure how well these nutrients enter the bloodstream when paired with different foods.See study design
What are the potential side effects?
Since this trial involves common foods like eggs and spinach without any experimental drugs involved, side effects are expected to be minimal. However, individuals may experience typical food-related reactions based on personal sensitivities.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~0, 3, 4.5, 6, 7.5, 9, 12, 24, 36, 48, 72 hours post-ingestion of spinach
This trial's timeline: 3 weeks for screening, Varies for treatment, and 0, 3, 4.5, 6, 7.5, 9, 12, 24, 36, 48, 72 hours post-ingestion of spinach for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Estimated Absorption (%Dose) of Vitamin E
Estimated Absorption (%Dose) of Vitamin K
Vitamin E Bioavailability
+3 more
Secondary outcome measures
Chylomicron Vitamin E
Chylomicron Vitamin K
Elimination Rate of Vitamin E
+3 more
Other outcome measures
Malondialdehyde
Vitamin C

Trial Design

4Treatment groups
Experimental Treatment
Group I: Zero hard-boiled eggExperimental Treatment1 Intervention
Deuterium-labeled spinach containing 2 mg αT and 500 ug PQ will be ingested alone prior to the 72-h pharmacokinetics trial.
Group II: Vegetable oilExperimental Treatment1 Intervention
Deuterium-labeled spinach containing 2 mg αT and 500 ug PQ will be ingested with vegetable oil (9.6 g fat) prior to the 72-h pharmacokinetics trial.
Group III: Two hard-boiled eggsExperimental Treatment1 Intervention
Deuterium-labeled spinach containing 2 mg αT and 500 ug PQ will be ingested with two whole eggs (9.6 g fat) prior to the 72-h pharmacokinetics trial.
Group IV: Two egg whitesExperimental Treatment1 Intervention
Deuterium-labeled spinach containing 2 mg αT and 500 ug PQ will be ingested with two egg whites (0 g fat) prior to the 72-h pharmacokinetics trial.

Find a Location

Who is running the clinical trial?

Ohio State UniversityLead Sponsor
830 Previous Clinical Trials
505,610 Total Patients Enrolled
1 Trials studying Nutritional Requirements
10 Patients Enrolled for Nutritional Requirements

Media Library

Two egg whites (Nutritional Supplement) Clinical Trial Eligibility Overview. Trial Name: NCT04286321 — N/A
Nutritional Requirements Research Study Groups: Zero hard-boiled egg, Two hard-boiled eggs, Vegetable oil, Two egg whites
Nutritional Requirements Clinical Trial 2023: Two egg whites Highlights & Side Effects. Trial Name: NCT04286321 — N/A
Two egg whites (Nutritional Supplement) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04286321 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Achieving Nutritional Adequacy Of Vitamins E and K With An Egg/Plant-Based Food Pairing - Study 2
Richard Bruno 2021. "Achieving Nutritional Adequacy Of Vitamins E and K With An Egg/Plant-Based Food Pairing - Study 2". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04286321.
~1 spots leftby Aug 2024
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