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Probiotics for Tooth Decay
Study Summary
This trial will study how well probiotics and synbiotics work to control oral diseases, with a focus on preventing or treating cavities.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I have severe gum disease.I have taken antibiotics in the last 3 months.You are a smoker or use any tobacco products.I have no health issues preventing dental treatments.You have a weakened immune system.I have fewer than 20 teeth.I have a bleeding disorder or am on blood thinners.You cannot use any flavored products, like mint candies or chewing gum, one week before or during the study.I am taking medication that causes dry mouth.I have 20 natural teeth without crowns, not counting wisdom teeth.You have braces or other dental devices that can be taken out or are permanently attached to your teeth.I have no current or past signs of tooth decay.I have a condition that causes dry mouth.
- Group 1: Caries Free
- Group 2: Caries Free- Placebo
- Group 3: Caries Active
- Group 4: Caries Active- Placebo
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What is the primary objective of this clinical trial?
"This clinical trial, to be evaluated over a two week period, aims to evaluate the fluctuation in ADS levels from baseline and further assess the ability of bacteria present in oral samples taken at weeks 2, 4 and 8 to produce ammonia from arginine under varying environmental conditions. Secondary outcomes include observing changes in bacterial composition collected during these visits."
Is this research program open to individuals aged 80 or above?
"The inclusion requirements of this clinical trial states that participants must be between 18 and 65 years old. There are currently 55 studies underway specifically for those younger than 18, while 31 trials accommodate older adults over the age of 65."
Who is eligible to partake in this experiment?
"Eligible candidates for this clinical trial must be suffering from dental caries and between 18 to 65 years of age. Currently, the study seeks 170 participants."
Are there still openings for this trial?
"According to clinicaltrials.gov, this medical trial has ceased recruiting patients; although the initial listing was published in February 2017 and last updated on June 9th of 2022, it is no longer seeking participants. Fortunately, there are presently 103 other studies actively enrolling volunteers."
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