Age Group 1: patients aged 3 to 23 months for Pediatric Disorders

Medical University of South Carolina, Charleston, SC
Pediatric Disorders+2 More ConditionsGadopiclenol - Drug
Eligibility
< 18
All Sexes

Study Summary

This trial tests how a drug affects the body in babies up to 23 months old, given intravenously before a MRI.

Eligible Conditions
  • Pediatric Disorders
  • Body Dysmorphia
  • Central Nervous System Disorders

Treatment Effectiveness

Phase-Based Effectiveness

1 of 3
Phase 2

Study Objectives

7 Primary · 0 Secondary · Reporting Duration: A total of 3 blood samples per patient will be taken post-injection for PK analysis, one within each window (10-60 minutes, 2-4 hours and 6-8 hours).

Hour 8
Area Under the Curve
Elimination half-life
Total clearance
Volume of distribution
Concentration is simulated at 10 minutes post injection
Simulated concentrations at 10 minutes post injection
Concentration is simulated at 20 minutes post injection
Simulated concentrations at 20 minutes post injection
Concentration is simulated at 30 minutes post injection
Simulated concentrations at 30 minutes post injection

Trial Safety

Phase-Based Safety

2 of 3
This is further along than 68% of similar trials

Awards & Highlights

No Placebo Group
All patients enrolled in this trial will receive the new treatment.

Trial Design

3 Treatment Groups

Age Group 1: patients aged 3 to 23 months
1 of 3
Age Group 3: patients aged from birth to 27 days (term newborns)
1 of 3
Age Group 2: patients aged 28 days to less than 3 months
1 of 3

Experimental Treatment

50 Total Participants · 3 Treatment Groups

Primary Treatment: Age Group 1: patients aged 3 to 23 months · No Placebo Group · Phase 2

Age Group 1: patients aged 3 to 23 months
Drug
Experimental Group · 1 Intervention: Gadopiclenol · Intervention Types: Drug
Age Group 3: patients aged from birth to 27 days (term newborns)
Drug
Experimental Group · 1 Intervention: Gadopiclenol · Intervention Types: Drug
Age Group 2: patients aged 28 days to less than 3 months
Drug
Experimental Group · 1 Intervention: Gadopiclenol · Intervention Types: Drug

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: a total of 3 blood samples per patient will be taken post-injection for pk analysis, one within each window (10-60 minutes, 2-4 hours and 6-8 hours).

Who is running the clinical trial?

GuerbetLead Sponsor
62 Previous Clinical Trials
93,016 Total Patients Enrolled
Donna R Roberts, MDPrincipal InvestigatorMedical University of South Carolina, Division of Neuroradiology

Eligibility Criteria

Age < 18 · All Participants · 0 Total Inclusion Criteria

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Frequently Asked Questions

Are there still vacancies to participate in this research endeavor?

"Affirmative. According to clinicaltrials.gov, this experiment has been recruiting since September 21st 2022 and is still ongoing with the last update taking place on October 21st 2022. The research team are currently seeking 50 participants from two separate sites for their study." - Anonymous Online Contributor

Unverified Answer

What is the scale of participation in this trial?

"Affirmative, clinicaltrials.gov's information indicates that this experiment is still recruiting individuals. This initiative began on September 21st 2022 and was recently edited on October 21st 2022. For the study to be successful, 50 people must enroll from two different sites." - Anonymous Online Contributor

Unverified Answer

What risks do people in Age Group 1: patients aged 3 to 23 months face?

"Given the Phase 2 trial status of this medication, with some safety data but none regarding efficacy, our team at Power rated its safety for Age Group 1 (3 to 23 months) a score of two." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.