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Kinase Inhibitor

Pemigatinib 4.5 MG for Pancreatic Cancer

Phase 2
Waitlist Available
Led By Erkut Borazanci, MD
Research Sponsored by HonorHealth Research Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up initiation of study treatment up to study completion, up to 2 years
Awards & highlights

Study Summary

This trial will test if pemigatinib can help treat advanced adenosquamous carcinoma of the pancreas.

Eligible Conditions
  • Pancreatic Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~initiation of study treatment up to study completion, up to 2 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and initiation of study treatment up to study completion, up to 2 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Overall response rate of pemigatinib
Secondary outcome measures
Number of participants with treatment-related adverse events as assessed by CTCAE V4.0
Overall survival (OS)
Progression free survival (PFS)

Trial Design

1Treatment groups
Experimental Treatment
Group I: PemigatinibExperimental Treatment1 Intervention
Participants will be provided with a bottle of pemigatinib tablets on Day 1 of each cycle (one cycle = 21 days). A bottle contains 4.5 mg X 42 tablets total. Each pemigatinib bottle is sufficient for one cycle. Resupply will be provided as necessary on Day 1 of each cycle.

Find a Location

Who is running the clinical trial?

HonorHealth Research InstituteLead Sponsor
25 Previous Clinical Trials
906 Total Patients Enrolled
Incyte CorporationIndustry Sponsor
364 Previous Clinical Trials
55,165 Total Patients Enrolled
Erkut Borazanci, MDPrincipal InvestigatorHonorHealth Research Institute
7 Previous Clinical Trials
403 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Will this experiment's findings still be applicable to an older demographic?

"This particular clinical trial is only enrolling patients aged 18 to 100. For context, there are 86 other trials specifically for people under 18 and 3176 studies for patients over 65 years old."

Answered by AI

How manytotal participants are being accepted into this clinical trial?

"That is correct, the information available on clinicaltrials.gov does show that this study is still looking for test subjects. The trial was first advertised on 6/14/2022 and was last updated 8/8/2022. They are currently recruiting for 20 patients from 1 site."

Answered by AI

Has Pemigatinib 4.5 MG been cleared by the FDA for patient use?

"Since this is a phase 2 trial, there is only some data supporting the safety of Pemigatinib 4.5 MG. Consequently, our team has given it a score of 2."

Answered by AI

Are we still enrolling people for this research project?

"Yes, the data on clinicaltrials.gov says that this trial is actively recruiting participants. The clinical trial was originally posted on 6/14/2022 and was last edited on 8/8/2022. The trial is enrolling 20 participants across 1 location."

Answered by AI

Could I undergo the procedures in this experiment?

"This trial is seeking 20 individuals over the age of 18 who have been diagnosed with carcinoma. In addition to meeting the age requirement, participants must also: -Be male or female-Able to provide informed consent and comply with trial procedures-Histologically or cytologically confirmed adenosquamous carcinoma of the pancreas (ASCP) -Metastatic or unresectable ASCP patients who have progressed on at least one line of therapy -FGFR gene fusion, mutation, or rearrangement as determined by standard CLIA-certified FDA-approved genomic panel"

Answered by AI
~0 spots leftby Aug 2024