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ALPN-202 for Lymphoma (NEON-2 Trial)
NEON-2 Trial Summary
This trial will test how well increasing doses of a new drug work against advanced solid tumors or lymphoma in adults.
- Lymphoma
- Solid Tumors
NEON-2 Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2024 Phase 2 trial • 57 Patients • NCT03004183NEON-2 Trial Design
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Who is running the clinical trial?
Frequently Asked Questions
Does my current health status meet the criteria for this research trial?
"This clinical trial is accepting 29 adults aged 18-80 who have been diagnosed with lymphoma. The enrollees must also meet the following criteria: an ECOG performance status grade of 0-1, available tumor biopsy to represent their condition, life expectancy over 3 months and eligibility for treatment with a PD-1 or PD-L1 inhibitor, previous experience with at least 2 systemic anti-cancer therapies (lymphoma subjects only), recovery from non-laboratory toxicities resulting from prior anticancer therapy up to Grade ≤ 1 (with exceptions like alopecia and hearing loss) and adequate baseline function in terms of he"
Does this clinical trial include geriatric participants?
"Participants in this medical trial must be between the ages of 18 and 80. However, there are 587 trials specifically for minors and 4705 clinical studies targeting those aged 65 or over."
To what extent could ALPN-202 put patients at risk?
"As this is a phase 1 trial, the safety of ALPN-202 has been approximated at 1 on the scale of 1 to 3 due to limited clinical data regarding its efficacy and security."
What pathologies have been most effectively addressed by ALPN-202?
"ALPN-202 is commonly prescribed for the treatment of cancerous tumors, but can also be employed to combat unresectable melanoma and microsatellite instability high in addition to disease progression from chemotherapy."
How many individuals are partaking in this research endeavor?
"At the present moment, this research project is not seeking out any new participants. This clinical trial was originally published on June 22nd 2021 and had its most recent update on November 8th 2022. For those looking for other options, there are 4059 studies actively recruiting patients with lymphoma and 961 trials that require ALPN-202 participants."
How many sites are currently hosting this trial?
"Currently, this medical trial is being conducted in 7 locations - with Boston, Cleveland and Grand Rapids among them. To limit travel needs while taking part in the study, it's important to select a site closest to you."
Are new volunteers still being accepted for the research program?
"This trial is no longer accepting participants; the original posting was made on June 22nd 2021, and it had its last amendment recorded on November 8th 2022. Alternative studies for lymphoma are abundant with 4059 clinical trials actively enrolling patients and 961 trials recruiting interested individuals to take part in ALPN-202 research."
What other investigations have been conducted concerning ALPN-202?
"As of the present time, there are 961 ongoing studies for ALPN-202 with 122 trials in Phase 3. Houston, Texas is a primary hub for these clinical trials but they can also be found across 35731 unique locations worldwide."
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